# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2423305 | A | Half life in human plasma at 1 uM by LC-MS/MS analysis | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
2. | ALA2423306 | A | Cytotoxicity against HEK293 cells after 24 hrs | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA2423307 | A | Half life in rat plasma at 1 uM by LC-MS/MS analysis | Rattus norvegicus | 1 | cell-free format | Scientific Literature | ||
4. | ALA2423308 | A | Half life in human liver S9 fraction at 1 uM by LC-MS/MS analysis | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
5. | ALA2423309 | A | Inhibition of CYP3A4 (unknown origin) using 7-benzyloxy trifluoromethylcoumarin as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA2423310 | B | Inhibition of rat CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
7. | ALA2423311 | B | Selectivity factor, ratio of IC50 for CYP3A4 (unknown origin) to IC50 for human CYP11B1 | Homo sapiens | 1 | assay format | Scientific Literature | ||
8. | ALA2423312 | A | Inhibition of CYP2A6 (unknown origin) using coumarin as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
9. | ALA2423313 | B | Inhibition of microsomal CYP19 in human placenta using [1beta-3H]-androstenedione as substrate at 2 uM by 3H2O method relative to control | Homo sapiens | 4 | assay format | Scientific Literature | ||
10. | ALA2423495 | B | Inhibition of human CYP17 expressed in Escherichia coli co-expressing rat NADPH-P450 reductase using progesterone as substrate at 2 uM relative to control | Homo sapiens | 4 | assay format | Scientific Literature | ||
11. | ALA2423496 | B | Ratio of 5-((1H-imidazol-1-yl)methyl)-2-phenylpyridine IC50 to compound IC50 for human CYP11B1 expressed in hamster V79MZh cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA2423497 | B | Selectivity factor, ratio of IC50 for human CYP11B2 to IC50 for human CYP11B1 | Homo sapiens | 31 | assay format | Scientific Literature | ||
13. | ALA2423498 | B | Inhibition of human CYP11B2 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
14. | ALA2423499 | B | Inhibition of human CYP11B1 expressed in hamster V79MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
15. | ALA2423500 | A | Half life in rat liver S9 fraction at 1 uM by LC-MS/MS analysis | Rattus norvegicus | 1 | subcellular format | Scientific Literature | ||
16. | ALA3424479 | B | Inhibition of human CYP11B1 expressed in hamster fibroblast using 100 nM [3H]-11-deoxycorticosterone as substrate after 25 mins by HPLC analysis | Homo sapiens | 30 | assay format | Scientific Literature | ||
17. | ALA3424480 | B | Inhibition of human CYP11B2 expressed in hamster fibroblast using 100 nM [3H]-11-deoxycorticosterone as substrate after 45 mins by HPLC analysis | Homo sapiens | 30 | assay format | Scientific Literature | ||
18. | ALA3424481 | B | Inhibition of human CYP19 expressed in hamster fibroblast using 500 nM [1beta-3H] androstenedione as substrate by HPLC analysis | Homo sapiens | 16 | assay format | Scientific Literature | ||
19. | ALA3424482 | B | Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysis | Rattus norvegicus | 14 | assay format | Scientific Literature | ||
20. | ALA3424483 | B | Selectivity index, ratio of IC50 for human CYP11B2 to IC50 for human CYP11B1 | Homo sapiens | 30 | assay format | Scientific Literature |