# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2421632 | T | Toxicity in mouse S180 cells xenografted mouse assessed as change on body weight at 5 mg/kg, po qd for 10 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
2. | ALA2421633 | T | Toxicity in mouse S180 cells xenografted mouse assessed as change on body weight at 1 mg/kg, po qd for 10 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
3. | ALA2421634 | T | Toxicity in mouse S180 cells xenografted mouse assessed as mortality at 20 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
4. | ALA2421635 | F | Antitumor activity against mouse S180 cells xenografted in mouse assessed as inhibition of tumor growth at 5 mg/kg, po qd for 10 days relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
5. | ALA2421636 | F | Antitumor activity against mouse S180 cells xenografted in mouse assessed as inhibition of tumor growth at 1 mg/kg, po qd for 10 days relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
6. | ALA2421637 | B | Inhibition of PI3K in human HCT116 cells assessed as reduction of AKT phosphorylation at Ser473 at 10 uM after 1 hr by by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA2421638 | F | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
8. | ALA2421639 | F | Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
9. | ALA2421640 | F | Antiproliferative activity against human U87MG cells after 48 hrs by MTT assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
10. | ALA3602349 | T | Acute toxicity in po dosed mouse | Mus musculus | 4 | organism-based format | Scientific Literature |