# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2422844 | Binding | Inhibition of recombinant Escherichia coli FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic phosphate up to 600 uM after 10 mins by malachite green-phosphomolybdate colorimetric assay in presence of triton X-100 | Escherichia coli | 2 | ALA2417459 | assay format | Scientific Literature | |
2. | ALA2422845 | Binding | Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic phosphate up to 600 uM after 20 mins by malachite green-phosphomolybdate colorimetric assay in presence of triton X-100 | Staphylococcus aureus | 2 | ALA2417459 | assay format | Scientific Literature | |
3. | ALA2423033 | Binding | Inhibition of C-terminal YFP-fused Escherichia coli FtsZ transformed in Escherichia coli envA1 assessed as Z ring formation at 125 uM after 30 to 60 mins by fluorescence microscopic analysis | Escherichia coli | 1 | ALA2417459 | assay format | Scientific Literature | |
4. | ALA2423034 | Functional | Antibacterial activity against Escherichia coli BL21 (DE3) envA1 assessed as growth inhibition after 18 hrs by microbroth dilution method | Escherichia coli BL21(DE3) | 2 | ALA2417459 | assay format | Scientific Literature | |
5. | ALA2423035 | Binding | Inhibition of C-terminal YFP-fused Escherichia coli FtsZ cloned in Escherichia coli envA1 assessed as protein dispersion in from of patches throughout cytoplasm at 125 uM after 30 to 60 mins by fluorescence microscopic analysis | Escherichia coli | 1 | ALA2417459 | assay format | Scientific Literature | |
6. | ALA2423039 | Binding | Inhibition of recombinant Escherichia coli FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic phosphate after 10 mins by malachite green-phosphomolybdate colorimetric assay | Escherichia coli | 2 | ALA2417459 | assay format | Scientific Literature | |
7. | ALA2423040 | Binding | Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic phosphate after 20 mins by malachite green-phosphomolybdate colorimetric assay | Staphylococcus aureus | 2 | ALA2417459 | assay format | Scientific Literature | |
8. | ALA3418981 | Binding | Inhibition of Escherichia coli FtsZ GTPase activity | Escherichia coli | 6 | ALA3414448 | single protein format | Scientific Literature | |
9. | ALA3419168 | Functional | Antimicrobial activity against methicillin-resistant Staphylococcus aureus | Staphylococcus aureus | 2 | ALA3414448 | organism-based format | Scientific Literature | |
10. | ALA3419177 | Functional | Antimicrobial activity against multidrug-resistant Staphylococcus aureus | Staphylococcus aureus | 1 | ALA3414448 | organism-based format | Scientific Literature | |
11. | ALA3419178 | Functional | Antimicrobial activity against cancomycin-resistant Enterococcus | Enterococcus | 1 | ALA3414448 | organism-based format | Scientific Literature | |
12. | ALA3865855 | Functional | Antibacterial activity against Escherichia coli ATCC 25922 after 18 hrs by broth microdilution method | Escherichia coli | 22 | ALA3865781 | assay format | Scientific Literature | |
13. | ALA3865856 | Functional | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC BAA-41 after 18 hrs by broth microdilution method | Staphylococcus aureus | 22 | ALA3865781 | assay format | Scientific Literature | |
14. | ALA3865866 | Functional | Antimicrobial activity against vancomycin-resistant Enterococcus faecalis after 18 hrs by broth microdilution method | Enterococcus faecalis | 22 | ALA3865781 | assay format | Scientific Literature | |
15. | ALA3865867 | Functional | Antimicrobial activity against vancomycin-sensitive Enterococcus faecalis after 18 hrs by broth microdilution method | Enterococcus faecalis | 22 | ALA3865781 | assay format | Scientific Literature | |
16. | ALA3865868 | Functional | Antibacterial activity against Klebsiella pneumoniae ATCC BAA-1144 after 18 hrs by broth microdilution method | Klebsiella pneumoniae | 22 | ALA3865781 | assay format | Scientific Literature | |
17. | ALA3865869 | Functional | Antibacterial activity against methicillin-sensitive Staphylococcus aureus after 18 hrs by broth microdilution method | Staphylococcus aureus | 22 | ALA3865781 | assay format | Scientific Literature | |
18. | ALA4428172 | Binding | Inhibition of Escherichia coli FtsZ assessed as reduction in GTPase activity by malachite green assay | Escherichia coli | 3 | ALA4428024 | single protein format | Scientific Literature | |
19. | ALA4428174 | Functional | Antimicrobial activity against Staphylococcus aureus | Staphylococcus aureus | 6 | ALA4428024 | organism-based format | Scientific Literature | |
20. | ALA4428177 | Functional | Antimicrobial activity against methicillin resistant Staphylococcus aureus | Staphylococcus aureus | 2 | ALA4428024 | organism-based format | Scientific Literature |