# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3418981 | Binding | Inhibition of Escherichia coli FtsZ GTPase activity | Escherichia coli | 6 | ALA3414448 | single protein format | Scientific Literature | |
2. | ALA3419179 | Functional | Antimicrobial activity against Staphylococcus aureus UAMS1 | Staphylococcus aureus | 2 | ALA3414448 | organism-based format | Scientific Literature | |
3. | ALA3419180 | Functional | Antimicrobial activity against community acquired methicillin-resistant Staphylococcus aureus USA300-LAC | Staphylococcus aureus | 2 | ALA3414448 | organism-based format | Scientific Literature | |
4. | ALA3419181 | Binding | Inhibition of Staphylococcus aureus FtsZ GTPase activity | Staphylococcus aureus | 2 | ALA3414448 | single protein format | Scientific Literature | |
5. | ALA2422844 | Binding | Inhibition of recombinant Escherichia coli FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic phosphate up to 600 uM after 10 mins by malachite green-phosphomolybdate colorimetric assay in presence of triton X-100 | Escherichia coli | 2 | ALA2417459 | assay format | Scientific Literature | |
6. | ALA2422845 | Binding | Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic phosphate up to 600 uM after 20 mins by malachite green-phosphomolybdate colorimetric assay in presence of triton X-100 | Staphylococcus aureus | 2 | ALA2417459 | assay format | Scientific Literature | |
7. | ALA2422850 | Binding | Inhibition of Bacillus subtilis SU570 GFP-fused FtsZ assessed as perturbation of Z-ring formation at 12 uM after 60 mins by fluorescence microscopic analysis | Bacillus subtilis | 1 | ALA2417459 | single protein format | Scientific Literature | |
8. | ALA2422851 | Binding | Inhibition of Bacillus subtilis FtsZ GTPase activity assessed as production of inorganic phosphate measured up to 60 mins by malachite green-phosphomolybdate colorimetric assay | Bacillus subtilis | 1 | ALA2417459 | single protein format | Scientific Literature | |
9. | ALA2422852 | Binding | Inhibition of C-terminal YFP-fused Escherichia coli FtsZ cloned in Escherichia coli envA1 assessed as protein dispersion in from of patches throughout cytoplasm at 340 uM after 30 to 60 mins by fluorescence microscopic analysis | Escherichia coli | 1 | ALA2417459 | assay format | Scientific Literature | |
10. | ALA2422853 | Binding | Inhibition of C-terminal YFP-fused Escherichia coli FtsZ cloned in Escherichia coli envA1 assessed as Z ring formation at 340 uM after 30 to 60 mins by fluorescence microscopic analysis | Escherichia coli | 1 | ALA2417459 | assay format | Scientific Literature | |
11. | ALA2423034 | Functional | Antibacterial activity against Escherichia coli BL21 (DE3) envA1 assessed as growth inhibition after 18 hrs by microbroth dilution method | Escherichia coli BL21(DE3) | 2 | ALA2417459 | assay format | Scientific Literature | |
12. | ALA2423036 | Binding | Displacement of [3H]-GTP from Bacillus subtilis FtsZ assessed as equilibrium association constant by scintillation counting assay | Bacillus subtilis | 1 | ALA2417459 | single protein format | Scientific Literature | |
13. | ALA2423037 | Binding | Displacement of mant-GTP from Bacillus subtilis FtsZ by fluorescence anisotropy analysis | Bacillus subtilis | 1 | ALA2417459 | single protein format | Scientific Literature | |
14. | ALA2423038 | Binding | Displacement of mant-GTP from Bacillus subtilis FtsZ assessed as equilibrium association constant by fluorescence anisotropy analysis | Bacillus subtilis | 1 | ALA2417459 | single protein format | Scientific Literature | |
15. | ALA2423039 | Binding | Inhibition of recombinant Escherichia coli FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic phosphate after 10 mins by malachite green-phosphomolybdate colorimetric assay | Escherichia coli | 2 | ALA2417459 | assay format | Scientific Literature | |
16. | ALA2423040 | Binding | Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic phosphate after 20 mins by malachite green-phosphomolybdate colorimetric assay | Staphylococcus aureus | 2 | ALA2417459 | assay format | Scientific Literature | |
17. | ALA3865855 | Functional | Antibacterial activity against Escherichia coli ATCC 25922 after 18 hrs by broth microdilution method | Escherichia coli | 22 | ALA3865781 | assay format | Scientific Literature | |
18. | ALA3865856 | Functional | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC BAA-41 after 18 hrs by broth microdilution method | Staphylococcus aureus | 22 | ALA3865781 | assay format | Scientific Literature | |
19. | ALA3865866 | Functional | Antimicrobial activity against vancomycin-resistant Enterococcus faecalis after 18 hrs by broth microdilution method | Enterococcus faecalis | 22 | ALA3865781 | assay format | Scientific Literature | |
20. | ALA3865867 | Functional | Antimicrobial activity against vancomycin-sensitive Enterococcus faecalis after 18 hrs by broth microdilution method | Enterococcus faecalis | 22 | ALA3865781 | assay format | Scientific Literature |