| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2422854 | F | Induction of human K562 cell differentiation at 5 uM after 72 hrs by trypan blue exclusion assay in presence of guanosine | Homo sapiens | 1 | ALA2417359 | cell-based format | Scientific Literature | |
| 2. | ALA2422858 | F | Antiproliferative activity against human K562 cells at 5 uM in presence of guanosine | Homo sapiens | 2 | ALA2417359 | cell-based format | Scientific Literature | |
| 3. | ALA2422862 | B | Inhibition of HDAC in human K562 cells using Boc-Lys[Ac]-AMC as substrate at 10 uM incubated for 10 mins prior to substrate addition measured after 80 mins by fluorescence assay | Homo sapiens | 4 | ALA2417359 | cell-based format | Scientific Literature | |
| 4. | ALA2422863 | B | Selectivity index, ratio of IC50 for human IMPDH1 to IC50 for human IMPDH2 | Homo sapiens | 3 | ALA2417359 | assay format | Scientific Literature | |
| 5. | ALA2422864 | B | Inhibition of human IMPDH1 | Homo sapiens | 3 | ALA2417359 | single protein format | Scientific Literature | |
| 6. | ALA2422865 | B | Inhibition of human IMPDH2 | Homo sapiens | 3 | ALA2417359 | single protein format | Scientific Literature | |
| 7. | ALA2422866 | F | Antiproliferative activity against human K562 cells at 5 uM | Homo sapiens | 2 | ALA2417359 | cell-based format | Scientific Literature | |
| 8. | ALA2422870 | F | Cytotoxicity against human K562 cells | Homo sapiens | 10 | ALA2417359 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!