# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2423241 | Functional | Cytotoxicity against human A2058 cells assessed as reduction of cell number at 30 uM after 24 hrs by MTS assay | Homo sapiens | 6 | ALA2417420 | cell-based format | Scientific Literature | |
2. | ALA2423242 | Binding | Activation of C-terminal FLAG-tagged human recombinant autotaxin using paranitrophenyl thymidine monophosphate as substrate measured every 2 mins by FRET assay | Homo sapiens | 3 | ALA2417420 | single protein format | Scientific Literature | |
3. | ALA2423243 | Binding | Inhibition of C-terminal FLAG-tagged human recombinant autotaxin using paranitrophenyl thymidine monophosphate as substrate at 10 uM measured every 2 mins by FRET assay relative to control | Homo sapiens | 8 | ALA2417420 | single protein format | Scientific Literature | |
4. | ALA2423244 | Binding | Competitive inhibition of C-terminal FLAG-tagged human recombinant autotaxin using synthetic substrate FS-3 by Michaelis-Menten equation analysis | Homo sapiens | 8 | ALA2417420 | single protein format | Scientific Literature | |
5. | ALA2423245 | Binding | Inhibition of C-terminal FLAG-tagged human recombinant autotaxin using synthetic substrate FS-3 measured every 2 mins by FRET assay | Homo sapiens | 14 | ALA2417420 | single protein format | Scientific Literature | |
6. | ALA2423246 | Binding | Inhibition of C-terminal FLAG-tagged human recombinant autotaxin using synthetic substrate FS-3 at 10 uM measured every 2 mins by FRET assay relative to control | Homo sapiens | 189 | ALA2417420 | single protein format | Scientific Literature |