# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2423163 | F | Cytotoxicity against human A2780 cells after 72 hrs by sulforhodamine B assay in presence of NMN | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
2. | ALA2423348 | P | Aqueous solubility of the compound in PBS buffer at 100 uM after 24 hrs at pH 7.4 by LC/CLND analysis | 36 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA2423349 | B | Inhibition of human NAMPT using NAM/PRPP as substrate incubated for 15 mins prior to substrate addition measured after 30 mins by mass spectrometric analysis | Homo sapiens | 36 | single protein format | Scientific Literature | ||
4. | ALA2423350 | F | Cytotoxicity against human A2780 cells after 72 hrs by sulforhodamine B assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
5. | ALA2423677 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 1 uM after 30 mins LC-MS analysis | Homo sapiens | 59 | microsome format | Scientific Literature | ||
6. | ALA2423678 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining at 1 uM after 30 mins LC-MS analysis | Mus musculus | 59 | microsome format | Scientific Literature | ||
7. | ALA2423679 | F | Antiproliferative activity against human A2780 cells assessed as growth inhibition after 72 hrs by SRB-based microplate reader analysis | Homo sapiens | 60 | cell-based format | Scientific Literature | ||
8. | ALA2423680 | B | Inhibition of C-terminal His-tagged NAMPT (unknown origin) expressed in Escherichia coli BL21 using nicotinamide as substrate preincubated for 15 mins before substrate addition measured after 30 mins by mass spectrometry-based assay | Homo sapiens | 60 | assay format | Scientific Literature | ||
9. | ALA3100989 | A | Metabolic stability of the compound in human liver microsomes assessed as compound remaining at 1 uM after 30 mins | Homo sapiens | 14 | assay format | Scientific Literature | ||
10. | ALA3100990 | A | Metabolic stability of the compound in mouse liver microsomes assessed as compound remaining at 1 uM after 30 mins | Mus musculus | 14 | microsome format | Scientific Literature | ||
11. | ALA3100991 | F | Antiproliferative activity against human A2780 cells after 72 hrs by sulforhodamine B assay in presence of nicotinamide mononucleotide | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
12. | ALA3100992 | F | Antiproliferative activity against human A2780 cells after 72 hrs by sulforhodamine B assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
13. | ALA3100993 | B | Inhibition of Nampt (unknown origin) using nicotinamide as substrate preincubated for 15 mins measured after 30 mins by mass spectrometry analysis | Homo sapiens | 14 | single protein format | Scientific Literature |