| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2423153 | A | Fraction unbound in mouse plasma at 5 uM after 4 hrs by equilibrium dialysis method | Mus musculus | 6 | cell-free format | Scientific Literature | ||
| 2. | ALA2423154 | A | Apparent permeability across apical to basolateral side in MDCK cells at 10 uM by LC-MS/MS analysis | Canis lupus familiaris | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA2423163 | F | Cytotoxicity against human A2780 cells after 72 hrs by sulforhodamine B assay in presence of NMN | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 4. | ALA2423172 | A | Clearance in CD-1 mouse hepatocytes at 1 uM after 3 hrs by LC-MS/MS analysis | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA2423173 | A | Clearance in CD-1 mouse liver microsomes at 1 uM after 60 mins by LC-MS/MS analysis | Mus musculus | 6 | microsome format | Scientific Literature | ||
| 6. | ALA2423174 | A | Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate by LC-MS/MS analysis | Homo sapiens | 6 | microsome format | Scientific Literature | ||
| 7. | ALA2423175 | A | Inhibition of CYP2C9 in human liver microsomes using (S)- warfarin as substrate by LC-MS/MS analysis | Homo sapiens | 6 | microsome format | Scientific Literature | ||
| 8. | ALA2423176 | A | Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate by LC-MS/MS analysis | Homo sapiens | 6 | microsome format | Scientific Literature | ||
| 9. | ALA2423177 | A | Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate by LC-MS/MS analysis | Homo sapiens | 6 | microsome format | Scientific Literature | ||
| 10. | ALA2423343 | A | Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate by LC-MS/MS analysis | Homo sapiens | 6 | microsome format | Scientific Literature | ||
| 11. | ALA2423344 | A | Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysis | Homo sapiens | 6 | microsome format | Scientific Literature | ||
| 12. | ALA2423345 | A | Time dependent inhibition of CYP3A4 in human liver microsomes using testosterone as substrate assessed as AUC shift of inhibition at 0.1 to 10 uM | Homo sapiens | 6 | microsome format | Scientific Literature | ||
| 13. | ALA2423346 | A | Time dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate assessed as AUC shift of inhibition at 0.1 to 10 uM | Homo sapiens | 6 | microsome format | Scientific Literature | ||
| 14. | ALA2423347 | A | Clearance in human liver microsomes at 1 uM after 60 mins by LC-MS/MS analysis | Homo sapiens | 27 | microsome format | Scientific Literature | ||
| 15. | ALA2423348 | P | Aqueous solubility of the compound in PBS buffer at 100 uM after 24 hrs at pH 7.4 by LC/CLND analysis | 36 | small-molecule physicochemical format | Scientific Literature | |||
| 16. | ALA2423349 | B | Inhibition of human NAMPT using NAM/PRPP as substrate incubated for 15 mins prior to substrate addition measured after 30 mins by mass spectrometric analysis | Homo sapiens | 36 | single protein format | Scientific Literature | ||
| 17. | ALA2423350 | F | Cytotoxicity against human A2780 cells after 72 hrs by sulforhodamine B assay | Homo sapiens | 36 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!