| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2421875 | F | Anticoagulant activity in Sprague-Dawley rat deep vein thrombosis model assessed as reduction in wet clot weight at 50 ug/kg, iv administered as infusion | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA2421877 | A | Oral bioavailability in dog | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 3. | ALA2421878 | A | Oral bioavailability in rat | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 4. | ALA2421885 | P | Aqueous solubility of the compound at pH 6.62 | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA2421886 | P | Aqueous solubility of the compound at pH 7.35 | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA2421887 | P | Aqueous solubility of the compound at pH 4.7 | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA2421888 | P | Distribution coefficient, log D of the compound at pH 7 by potentiometric titration | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 8. | ALA2421889 | P | Dissociation constant, pKa of the compound by potentiometric titration | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 9. | ALA2421891 | A | Oral bioavailability in Beagle dog at 10 mg/kg | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA2421895 | A | Cmax in Beagle dog at 10 mg/kg, po | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA2421897 | A | Oral bioavailability in Sprague-Dawley rat at 30 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA2421900 | A | AUC in Sprague-Dawley rat at 30 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA2421903 | A | Cmax in Sprague-Dawley rat at 30 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA2421904 | F | Anticoagulant activity in rat assessed as blood loss at 2 X ED50 measured as hemoglobin level after 60 mins (Rvb = 0.37 +/- 0.19 mg/ml) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 15. | ALA2421905 | A | Oral bioavailability in monkey | Macaca mulatta | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA2421906 | F | Anticoagulant activity in rat assessed as blood loss at ED80 measured as hemoglobin level after 60 mins (Rvb = 0.37 +/- 0.19 mg/ml) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA2421907 | F | Anticoagulant activity in rat assessed as blood loss at ED50 measured as hemoglobin level after 60 mins (Rvb = 0.37 +/- 0.19 mg/ml) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA2421908 | F | Anticoagulant activity in rat assessed as time to first arrest of bleeding at 2 x ED50 measured after 45 mins (Rvb = 267 +/- 43.4 seconds) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA2421909 | F | Anticoagulant activity in rat assessed as time to first arrest of bleeding at ED80 measured after 45 mins (Rvb = 267 +/- 43.4 seconds) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA2421910 | F | Anticoagulant activity in rat assessed as time to first arrest of bleeding at ED50 measured after 45 mins (Rvb = 267 +/- 43.4 seconds) | Rattus norvegicus | 2 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!