# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2421268 | F | Antibacterial activity against Propionibacterium acnes PCM 2400 assessed as growth inhibition up to 250 ug/mL after 48 hrs by microplate Alamar blue assay | Cutibacterium acnes | 11 | organism-based format | Scientific Literature | ||
2. | ALA2423178 | F | Antibacterial activity against Propionibacterium acnes PCM 2400 assessed as growth inhibition after 48 hrs by microplate Alamar blue assay | Cutibacterium acnes | 15 | organism-based format | Scientific Literature | ||
3. | ALA2423181 | F | Antibacterial activity against Mycobacterium tuberculosis H37Rv assessed as growth inhibition at 6.25 ug/mL by BACTEC 460 radiometric assay relative to control | Mycobacterium tuberculosis | 14 | organism-based format | Scientific Literature | ||
4. | ALA3626888 | B | Inhibition of recombinant human KAT2B catalytic domain using biotinylated histone H3 (1 to 21 amino acid residues) as substrate at 50 uM preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 28 | single protein format | Scientific Literature | ||
5. | ALA3626890 | B | Inhibition of recombinant human KAT2A using biotinylated histone H3 (1 to 21 amino acid residues) as substrate at 50 uM preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 28 | single protein format | Scientific Literature | ||
6. | ALA3626892 | B | Inhibition of recombinant human CBP using biotinylated histone H3 (1 to 21 amino acid residues) as substrate at 50 uM preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 15 | single protein format | Scientific Literature | ||
7. | ALA3626893 | B | Inhibition of recombinant human CBP using biotinylated histone H3 (1 to 21 amino acid residues) as substrate preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 9 | single protein format | Scientific Literature | ||
8. | ALA3626894 | B | Inhibition of recombinant human p300 using biotinylated histone H3 (1 to 21 amino acid residues) as substrate at 50 uM preincubated for 10 mins followed by acetyl-CoA addition measured after 10 mins by time resolved fluorescence assay | Homo sapiens | 28 | single protein format | Scientific Literature | ||
9. | ALA3626897 | F | Cytotoxicity against human LNCAP cells assessed as growth inhibition after 72 hrs by MTS assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
10. | ALA3626898 | F | Cytotoxicity against human HL60 cells assessed as growth inhibition after 72 hrs by MTS assay | Homo sapiens | 7 | cell-based format | Scientific Literature |