# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2423199 | B | Inhibition of MRP1 (unknown origin) expressed in human 2008 cells assessed as calcein-AM accumulation preincubated for 30 mins before calcein-AM addition measured up to 90 mins by fluorescence assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
2. | ALA2423200 | B | Inhibition of p-glycoprotein (unknown origin) expressed in human A2780Adr cells assessed as calcein-AM accumulation preincubated for 30 mins before calcein-AM addition measured up to 90 mins by fluorescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
3. | ALA2423205 | B | Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition measured after 120 mins by flow cytometry | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
4. | ALA2423207 | B | Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of Hoechst 33342 preincubated for 30 mins before Hoechst 33342 addition measured after 120 mins by fluorescence assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
5. | ALA3232358 | A | Inhibition of benzo(alpha)pyrene monooxygenase in 3-methylcholanthrene-treated Sprague-Dawley rat liver microsomes using [3H]benzo(alpha)pyrene as substrate after 15 mins by liquid scintillation spectrometry | Rattus norvegicus | 13 | assay format | Scientific Literature | ||
6. | ALA3232361 | A | Inhibition of benzo(alpha)pyrene monooxygenase in 3-methylcholanthrene-treated Sprague-Dawley rat liver microsomes using [3H]benzo(alpha)pyrene as substrate at 100 uM after 15 mins by liquid scintillation spectrometry | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
7. | ALA3232364 | A | Inhibition of benzo(alpha)pyrene monooxygenase in phenobarbital-treated Sprague-Dawley rat liver microsomes using [3H]benzo(alpha)pyrene as substrate after 15 mins by liquid scintillation spectrometry | Rattus norvegicus | 13 | assay format | Scientific Literature | ||
8. | ALA3232367 | A | Inhibition of benzo(alpha)pyrene monooxygenase in phenobarbital-treated Sprague-Dawley rat liver microsomes using [3H]benzo(alpha)pyrene as substrate at 100 uM after 15 mins by liquid scintillation spectrometry | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
9. | ALA4004370 | B | Inhibition of porcine cholesterol esterase at 1 nM using para-nitrophenyl butyrate as substrate after 5 mins in presence of sodium taurocholate by spectrophotometric method relative to control | Sus scrofa | 40 | single protein format | Scientific Literature | ||
10. | ALA4004371 | B | Inhibition of porcine cholesterol esterase at 5 nM using para-nitrophenyl butyrate as substrate after 5 mins in presence of sodium taurocholate by spectrophotometric method relative to control | Sus scrofa | 40 | single protein format | Scientific Literature | ||
11. | ALA4004372 | B | Inhibition of porcine cholesterol esterase at 10 nM using para-nitrophenyl butyrate as substrate after 5 mins in presence of sodium taurocholate by spectrophotometric method relative to control | Sus scrofa | 40 | single protein format | Scientific Literature | ||
12. | ALA4004373 | B | Inhibition of porcine cholesterol esterase at 25 nM using para-nitrophenyl butyrate as substrate after 5 mins in presence of sodium taurocholate by spectrophotometric method relative to control | Sus scrofa | 40 | single protein format | Scientific Literature | ||
13. | ALA4004374 | B | Inhibition of porcine cholesterol esterase at 50 nM using para-nitrophenyl butyrate as substrate after 5 mins in presence of sodium taurocholate by spectrophotometric method relative to control | Sus scrofa | 40 | single protein format | Scientific Literature | ||
14. | ALA4004375 | B | Inhibition of porcine cholesterol esterase using para-nitrophenyl butyrate as substrate after 5 mins in presence of sodium taurocholate by spectrophotometric method | Sus scrofa | 40 | single protein format | Scientific Literature | ||
15. | ALA4311582 | B | Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate assessed as percent enzyme activity at 1 uM after 30 mins in presence of NADPH by EROD assay relative to control | Homo sapiens | 51 | single protein format | Scientific Literature | ||
16. | ALA4311583 | A | Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate assessed as percent enzyme activity at 1 uM after 15 mins in presence of NADPH by EROD assay relative to control | Homo sapiens | 51 | single protein format | Scientific Literature | ||
17. | ALA4311584 | A | Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate assessed as percent enzyme activity at 1 uM after 30 mins in presence of NADPH by EROD assay relative to control | Homo sapiens | 51 | single protein format | Scientific Literature | ||
18. | ALA4380057 | B | Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and NADPH-generating system incubated for 35 mins by fluorometry | Homo sapiens | 42 | single protein format | Scientific Literature | ||
19. | ALA4380058 | A | Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and NADPH-generating system incubated for 15 mins by fluorometry | Homo sapiens | 42 | single protein format | Scientific Literature | ||
20. | ALA4380059 | A | Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and NADPH-generating system incubated for 50 mins by fluorometry | Homo sapiens | 42 | single protein format | Scientific Literature |