# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2423208 | B | Inhibition of Trypanosoma cruzi cruzain expressed in Escherichia coli DH5-alpha using Bz-Phe-Arg-AMC as substrate at 10 uM preincubated for 5 mins followed by substrate addition measured for 5 mins by spectrofluorimetric analysis relative to control | Trypanosoma cruzi | 13 | assay format | Scientific Literature | ||
2. | ALA2423210 | T | Mutagenicity in Swiss albino mouse at 250 mg/kg after 30 hrs by micronucleus test | Mus musculus | 3 | organism-based format | Scientific Literature | ||
3. | ALA2423211 | T | Mutagenicity in Swiss albino mouse at 100 mg/kg after 30 hrs by micronucleus test | Mus musculus | 4 | organism-based format | Scientific Literature | ||
4. | ALA2423212 | F | Potency index, ratio of benznidazole IC50 to compound IC50 for epimastigote stage of Trypanosoma cruzi Y | Trypanosoma cruzi | 1 | organism-based format | Scientific Literature | ||
5. | ALA2423383 | F | Trypanocidal activity against epimastigote stage of Trypanosoma cruzi Y after 72 hrs by MTT assay | Trypanosoma cruzi | 13 | organism-based format | Scientific Literature |