# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2424393 | A | Cytotoxicity against rat L6 cells after 72 hrs by Alamar Blue assay | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
2. | ALA2424394 | T | Selectivity index, ratio of EC50 for rat L6 cells to EC50 for Plasmodium falciparum K1 | 20 | cell-based format | Scientific Literature | |||
3. | ALA2424395 | B | Selectivity index, ratio of Ki for human dUTPase to Ki for recombinant Plasmodium falciparum dUTPase | 14 | assay format | Scientific Literature | |||
4. | ALA2424396 | F | Antiparasitic activity against chloroquine/pyrimethamine-resistant Plasmodium falciparum K1 infected in erythrocytes assessed as parasite growth inhibition after 48 hrs by [3H]-hypoxanthine incorporation assay | Plasmodium falciparum | 15 | organism-based format | Scientific Literature | ||
5. | ALA2424397 | B | Inhibition of recombinant human dUTPase expressed in Escherichia coli BL21 (DE3) using dUTP as substrate by spectrophotometric analysis | Homo sapiens | 14 | assay format | Scientific Literature | ||
6. | ALA2424398 | B | Inhibition of recombinant Plasmodium falciparum dUTPase expressed in Escherichia coli BL21 (DE3) using dUTP as substrate by spectrophotometric analysis | Plasmodium falciparum | 14 | assay format | Scientific Literature |