# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2422388 | B | Activity at recombinant ERAP1 (unknown origin) expressed in baculovirus-infected Hi5 insect cells assessed as compound hydrolysis at 10 uM after 7 to 30 mins by RP-HPLC analysis | Homo sapiens | 1 | ALA2417496 | cell-based format | Scientific Literature | |
2. | ALA2422389 | B | Competitive inhibition of recombinant ERAP1 (unknown origin) expressed in baculovirus-infected Hi5 insect cells using L-Leucine-para-nitroanilide as substrate by Michaelis-Menten plot analysis | Homo sapiens | 1 | ALA2417496 | cell-based format | Scientific Literature | |
3. | ALA2422390 | B | Selectivity ratio of IC50 for recombinant ERAP2 (unknown origin) to IC50 for recombinant ERAP1 (unknown origin) | Homo sapiens | 1 | ALA2417496 | assay format | Scientific Literature | |
4. | ALA2422395 | B | Inhibition of human recombinant IRAP expressed in HeLa cells assessed as L-Leucine-7-amido-4-methyl coumarin hydrolysis to 7-amido-4-methyl coumarin after 5 to 10 mins by fluorescence assay | Homo sapiens | 11 | ALA2417496 | cell-based format | Scientific Literature | |
5. | ALA2422396 | B | Inhibition of recombinant ERAP2 (unknown origin) expressed in baculovirus-infected Hi5 insect cells assessed as L-Arginyl-7-amido-4-methyl coumarin hydrolysis to 7-amido-4-methyl coumarin after 5 to 10 mins by fluorescence assay | Homo sapiens | 7 | ALA2417496 | cell-based format | Scientific Literature | |
6. | ALA2422397 | B | Inhibition of recombinant ERAP1 (unknown origin) expressed in baculovirus-infected Hi5 insect cells assessed as L-Leucine-7-amido-4-methyl coumarin hydrolysis to 7-amido-4-methyl coumarin after 5 to 10 mins by fluorescence assay | Homo sapiens | 4 | ALA2417496 | cell-based format | Scientific Literature | |
7. | ALA3419985 | B | Inhibition of ERAP1 in mouse RAW264.7 cells assessed as reduction in interferon-gamma/LPS-induced phagocytosis after 24 hrs by fluorescent latex beads internalization assay | Mus musculus | 4 | ALA3414429 | cell-based format | Scientific Literature |