# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2428541 | Functional | Induction of apoptosis in human G361 cells | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
2. | ALA2428542 | Functional | Induction of autophagy in human G361 cells assessed as fragmentation of LC3 at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
3. | ALA2428543 | Functional | Downregulation of MDM2 protein expression in human G361 cells at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
4. | ALA2428544 | Functional | Downregulation of p53 protein expression in human G361 cells at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
5. | ALA2428545 | Functional | Induction of apoptosis in human G361 cells assessed as increase in p53 mRNA level | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
6. | ALA2428546 | Functional | Induction of apoptosis in human G361 cells assessed as increase in p53 protein level at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
7. | ALA2428547 | Functional | Induction of apoptosis in human G361 cells assessed as decrease in BCL-XL protein expression after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
8. | ALA2428548 | Functional | Induction of apoptosis in human G361 cells assessed as increase in BCL-2 protein expression at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
9. | ALA2428549 | Functional | Induction of apoptosis in human G361 cells assessed as decrease in caspase-7 zymogene at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
10. | ALA2428550 | Functional | Induction of apoptosis in human G361 cells assessed as PARP-1 cleavage at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
11. | ALA2428551 | Functional | Induction of apoptosis in human G361 cells assessed as decrease in caspase-3 zymogene at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
12. | ALA2428552 | Functional | Induction of apoptosis in human G361 cells assessed as caspase-9 cleavage at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
13. | ALA2428553 | Functional | Induction of apoptosis in human G361 cells assessed as caspase-3/7 activation at 2 uM after 24 hrs by fluorescence assay relative to control | Homo sapiens | 5 | ALA2424632 | cell-based format | Scientific Literature | |
14. | ALA2428554 | Binding | Inhibition of AKT phosphorylation at Ser473 in human G361 cells at 0.22 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
15. | ALA2428555 | Binding | Inhibition of ERK1/2 phosphorylation at Thr202/Tyr204 in human G361 cells at 0.22 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
16. | ALA2428556 | Functional | Upregulation of p27KIP1 protein expression in human G361 cells at 2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
17. | ALA2428557 | Functional | Upregulation of p27KIP1 protein expression in human G361 cells at 670 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
18. | ALA2428670 | Functional | Effect on cyclin E protein expression in human G361 cells at 0.22 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
19. | ALA2428671 | Functional | Effect on CDK2 protein expression in human G361 cells at 0.22 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature | |
20. | ALA2428672 | Functional | Effect on CDK1 protein expression in human G361 cells at 0.22 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA2424632 | cell-based format | Scientific Literature |