# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2428541 | F | Induction of apoptosis in human G361 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA2428542 | F | Induction of autophagy in human G361 cells assessed as fragmentation of LC3 at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA2428543 | F | Downregulation of MDM2 protein expression in human G361 cells at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA2428544 | F | Downregulation of p53 protein expression in human G361 cells at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA2428545 | F | Induction of apoptosis in human G361 cells assessed as increase in p53 mRNA level | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA2428546 | F | Induction of apoptosis in human G361 cells assessed as increase in p53 protein level at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA2428547 | F | Induction of apoptosis in human G361 cells assessed as decrease in BCL-XL protein expression after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA2428548 | F | Induction of apoptosis in human G361 cells assessed as increase in BCL-2 protein expression at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA2428549 | F | Induction of apoptosis in human G361 cells assessed as decrease in caspase-7 zymogene at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA2428550 | F | Induction of apoptosis in human G361 cells assessed as PARP-1 cleavage at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA2428551 | F | Induction of apoptosis in human G361 cells assessed as decrease in caspase-3 zymogene at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA2428552 | F | Induction of apoptosis in human G361 cells assessed as caspase-9 cleavage at 0.2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA2428553 | F | Induction of apoptosis in human G361 cells assessed as caspase-3/7 activation at 2 uM after 24 hrs by fluorescence assay relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
14. | ALA2428554 | B | Inhibition of AKT phosphorylation at Ser473 in human G361 cells at 0.22 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA2428555 | B | Inhibition of ERK1/2 phosphorylation at Thr202/Tyr204 in human G361 cells at 0.22 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA2428556 | F | Upregulation of p27KIP1 protein expression in human G361 cells at 2 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA2428557 | F | Upregulation of p27KIP1 protein expression in human G361 cells at 670 nM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA2428670 | F | Effect on cyclin E protein expression in human G361 cells at 0.22 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA2428671 | F | Effect on CDK2 protein expression in human G361 cells at 0.22 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA2428672 | F | Effect on CDK1 protein expression in human G361 cells at 0.22 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |