#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2426870	ADME	Prodrug activation in APP51/16 transgenic male mouse blood assessed as (1R,3R,4S,5S)-3-Amino-5-[4-amino-3-fluoro-5-((R)-2,2,2-trifluoro-1-methoxymethyl-ethoxy)-benzyl]-1-oxo-tetrahydro-thiopyran-4-ol level at 60 umol/kg, po after 4 hrs	Mus musculus	3	ALA2424550	organism-based format	Scientific Literature
2.	ALA2427016	Functional	Antialzheimer activity in APP51/16 transgenic male mouse assessed as reduction of amyloid beta 40 level in brain at 60 umol/kg, po after 4 hrs	Mus musculus	3	ALA2424550	organism-based format	Scientific Literature
3.	ALA2427018	ADME	Fraction unbound in APP51/16 transgenic male mouse brain at 60 umol/kg, po after 4 hrs	Mus musculus	1	ALA2424550	organism-based format	Scientific Literature
4.	ALA2427024	ADME	Drug level in APP51/16 transgenic male mouse brain at 60 umol/kg, po after 4 hrs	Mus musculus	3	ALA2424550	organism-based format	Scientific Literature
5.	ALA2427031	ADME	Prodrug activation in APP51/16 transgenic male mouse blood assessed as (1R,3S,4S,5R)-3-(4-Amino-3-fluoro-5-hydroxy-benzyl)-5-(3-tert-butyl-benzylamino)-1-oxo-tetrahydro-thiopyran-4-ol level at 60 umol/kg, po after 4 hrs	Mus musculus	3	ALA2424550	organism-based format	Scientific Literature
6.	ALA2427037	ADME	Drug level in APP51/16 transgenic male mouse blood at 60 umol/kg, po after 4 hrs	Mus musculus	3	ALA2424550	organism-based format	Scientific Literature
7.	ALA2427039	ADME	Clearance in mouse liver microsomes	Mus musculus	14	ALA2424550	microsome format	Scientific Literature
8.	ALA2427040	ADME	Clearance in human liver microsomes	Homo sapiens	14	ALA2424550	microsome format	Scientific Literature
9.	ALA2427043	ADME	Inhibition of CYP3A4 (unknown origin)	Homo sapiens	18	ALA2424550	single protein format	Scientific Literature
10.	ALA2427044	Physicochemical	Lipophilicity, log P of the compound		18	ALA2424550	small-molecule physicochemical format	Scientific Literature
11.	ALA2427046	ADME	Efflux ratio of permeability from apical to basolateral side over basolateral to apical side in MDCK2 cells expressing human MDR1	Canis lupus familiaris	20	ALA2424550	cell-based format	Scientific Literature
12.	ALA2427047	ADME	Apparent permeability of the compound in MDCK cells expressing human MDR1	Canis lupus familiaris	20	ALA2424550	cell-based format	Scientific Literature
13.	ALA2427049	Binding	Inhibition of BACE1 (unknown origin) expressed in CHO cells co-expressing wild type APP	Homo sapiens	20	ALA2424550	cell-based format	Scientific Literature
14.	ALA2427050	Binding	Inhibition of human cathepsin-D	Homo sapiens	20	ALA2424550	single protein format	Scientific Literature
15.	ALA2427051	Binding	Inhibition of human BACE1	Homo sapiens	22	ALA2424550	single protein format	Scientific Literature