# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2428717 | ADME | Drug uptake in P-gp-knockout rat cerebellum at 78.7 to 189.8 MBq, iv after 90 mins by PET analysis in presence of 10 mg/kg, po unlabeled compound | Rattus norvegicus | 3 | ALA2424641 | organism-based format | Scientific Literature | |
2. | ALA2428718 | ADME | Drug uptake in P-gp-knockout rat thalamus at 78.7 to 189.8 MBq, iv after 90 mins by PET analysis | Rattus norvegicus | 3 | ALA2424641 | organism-based format | Scientific Literature | |
3. | ALA2428722 | ADME | Ratio of flux ratio in pig LLC cells expressing MDR1 to flux ratio on pig LLC-PK1 cells | Sus scrofa | 6 | ALA2424641 | cell-based format | Scientific Literature | |
4. | ALA2428723 | ADME | Flux ratio of permeability from apical to basolateral to basolateral to apical side in pig LLC-PK1 cells after 2 hrs | Sus scrofa | 6 | ALA2424641 | cell-based format | Scientific Literature | |
5. | ALA2428729 | ADME | Drug uptake in P-gp-knockout rat hippocampus at 78.7 to 189.8 MBq, iv after 90 mins by PET analysis | Rattus norvegicus | 3 | ALA2424641 | organism-based format | Scientific Literature | |
6. | ALA2428730 | ADME | Drug uptake in P-gp-knockout rat neocortex at 78.7 to 189.8 MBq, iv after 90 mins by PET analysis | Rattus norvegicus | 3 | ALA2424641 | organism-based format | Scientific Literature | |
7. | ALA2428731 | Binding | Antagonist activity at melatonin MT1A receptor (unknown origin) expressed in HEK 293 cells coexpressing Gqi5 chimeric G-protein after 1 hr by fluorescence-based analysis | Homo sapiens | 2 | ALA2424641 | cell-based format | Scientific Literature | |
8. | ALA2428732 | Binding | Antagonist activity at cannabinoid CB1 receptor (unknown origin) expressed in HEK 293 cells coexpressing Gqi5 chimeric G-protein after 1 hr by fluorescence-based analysis | Homo sapiens | 2 | ALA2424641 | cell-based format | Scientific Literature | |
9. | ALA2428735 | Physicochemical | Octanol-phosphate buffer partition coefficient, log D of the compound at pH 7.4 by Shake flask method | 9 | ALA2424641 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA2428736 | ADME | Flux ratio of permeability from apical to basolateral to basolateral to apical side in pig LLC cells expressing MDR1 after 2 hrs | Sus scrofa | 6 | ALA2424641 | cell-based format | Scientific Literature | |
11. | ALA2428737 | Binding | Displacement of [125I]-orexin-A from human OX2 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis | Homo sapiens | 6 | ALA2424641 | cell-based format | Scientific Literature | |
12. | ALA2428738 | Binding | Displacement of [125I]-orexin-A from human OX1 receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysis | Homo sapiens | 6 | ALA2424641 | cell-based format | Scientific Literature |