| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2427432 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as net tumor log cell kill at 50 mg/kg, ip bid administered every other day started on day 14 followed by compound readministration every other day started on day 27 | Homo sapiens | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 2. | ALA2427433 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as tumor log cell kill at 75 mg/kg, ip qd administered every other day started on day 14 for 5 days followed by compound readministration on day 27 | Homo sapiens | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 3. | ALA2427434 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as net tumor log cell kill at 75 mg/kg, ip qd administered on day 14 for 5 days followed by compound readministration on day 27 | Homo sapiens | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 4. | ALA2427435 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as net tumor log cell kill at 50 mg/kg, ip qd administered on day 14 for 5 days followed by compound readministration on day 27 | Homo sapiens | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 5. | ALA2427436 | B | Displacement of [3H]-colchicine from pig brain tubulin at 5 uM after 10 mins by scintillation counting analysis relative to control | Sus scrofa | 3 | ALA2424583 | assay format | Scientific Literature | |
| 6. | ALA2427437 | B | Displacement of [3H]-colchicine from pig brain tubulin at 1 uM after 10 mins by scintillation counting analysis relative to control | Sus scrofa | 3 | ALA2424583 | assay format | Scientific Literature | |
| 7. | ALA2427438 | B | Inhibition of pig brain tubulin assembly preincubated for 15 mins followed by GTP addition measured after 20 mins by spectrophotometric analysis in presence of glycerol | Sus scrofa | 3 | ALA2424583 | assay format | Scientific Literature | |
| 8. | ALA2427439 | T | Toxicity in athymic nude mouse xenografted in human MDA-MB-231 cells assessed as mortality at 50 mg/kg, ip bid administered every other day started on day 14 followed by compound readministration every other day started on day 27 | Mus musculus | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 9. | ALA2427440 | T | Toxicity in athymic nude mouse xenografted in human MDA-MB-231 cells assessed as mortality at 75 mg/kg, ip qd administered every other day started on day 14 for 5 days followed by compound readministration on day 27 | Mus musculus | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 10. | ALA2427441 | T | Toxicity in athymic nude mouse xenografted in human MDA-MB-231 cells assessed as mortality at 75 mg/kg, ip qd administered on day 14 for 5 days followed by compound readministration on day 27 | Mus musculus | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 11. | ALA2427442 | T | Toxicity in athymic nude mouse xenografted in human MDA-MB-231 cells assessed as mortality at 50 mg/kg, ip qd administered on day 14 for 5 days followed by compound readministration on day 27 | Mus musculus | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 12. | ALA2427443 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as delay in tumor growth at 50 mg/kg, ip bid administered every other day started on day 14 followed by compound readministration every other day started on day 27 measured on day 31 relative to control | Homo sapiens | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 13. | ALA2427444 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as delay in tumor growth at 75 mg/kg, ip qd administered every other day started on day 14 for 5 days followed by compound readministration on day 27 measured on day 31 relative to control | Homo sapiens | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 14. | ALA2427445 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as delay in tumor growth at 75 mg/kg, ip qd administered on day 14 for 5 days followed by compound readministration on day 27 measured on day 31 relative to control | Homo sapiens | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 15. | ALA2427627 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as delay in tumor growth at 50 mg/kg, ip qd administered on day 14 for 5 days followed by compound readministration on day 27 measured on day 31 relative to control | Homo sapiens | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 16. | ALA2427628 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as tumor growth inhibition at 50 mg/kg, ip bid administered every other day started on day 14 followed by compound readministration every other day started on day 27 measured on day 31 relative to control | Homo sapiens | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 17. | ALA2427629 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as tumor growth inhibition at 75 mg/kg, ip qd administered every other day started on day 14 for 5 days followed by compound readministration on day 27 measured on day 31 relative to control | Homo sapiens | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 18. | ALA2427630 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as tumor growth inhibition at 75 mg/kg, ip qd administered on day 14 for 5 days followed by compound readministration on day 27 measured on day 31 relative to control | Homo sapiens | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 19. | ALA2427631 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as tumor growth inhibition at 50 mg/kg, ip qd administered on day 14 for 5 days followed by compound readministration on day 27 measured on day 31 relative to control | Homo sapiens | 1 | ALA2424583 | organism-based format | Scientific Literature | |
| 20. | ALA2427632 | T | Toxicity in athymic nude mouse xenografted in human MDA-MB-231 cells assessed as body weight loss at 50 mg/kg, ip bid administered every other day started on day 14 followed by compound readministration every other day started on day 27 (Rvb = 6.7%) | Mus musculus | 1 | ALA2424583 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!