| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2429407 | A | Cytotoxicity against african green monkey Vero cells at 25 uM | Chlorocebus sabaeus | 20 | cell-based format | Scientific Literature | ||
| 2. | ALA2429408 | A | Cytotoxicity against human SH-SY5Y cells at 25 uM | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 3. | ALA2429409 | A | Cytotoxicity against rat PC12 cells at 25 uM | Rattus norvegicus | 20 | cell-based format | Scientific Literature | ||
| 4. | ALA2429414 | B | Inhibition of PARP1 (unknown origin) up to 25 uM | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 5. | ALA2427119 | B | Inhibition of HDAC6 in rat PC12 cells assessed as acetylation of histone H3 at 10 uM after 48 hrs by Western blotting analysis | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA2427121 | B | Inhibition of HDAC6 in rat PC12 cells assessed as induction of alpha-tubulin acetylation at 10 uM after 48 hrs by Western blotting analysis | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA2427125 | F | Induction iof GAP-43 protein expression in rat PC12 cells after 48 hrs by Western blotting analysis | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA2427126 | F | Increase of synaptic activity in human SH-SY5Y cells after 5 days by fluorescence assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 9. | ALA2427127 | F | Induction of neurite outgrowth in human SH-SY5Y cells after 5 days | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 10. | ALA2427128 | F | Increase of synaptic activity in rat PC12 cells after 5 days by fluorescence assay | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
| 11. | ALA2427129 | F | Induction of neurite outgrowth in human SH-SY5Y cells at 10 uM after 5 days | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 12. | ALA2427130 | F | Induction of neurite outgrowth in rat PC12 cells after 5 days | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
| 13. | ALA2427132 | F | Induction of neurite outgrowth in rat PC12 cells at 10 uM after 5 days | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
| 14. | ALA2427133 | B | Selectivity index, ratio of IC50 for human recombinant HDAC1 to IC50 for human recombinant HDAC6 | Homo sapiens | 22 | assay format | Scientific Literature | ||
| 15. | ALA2427134 | B | Selectivity index, ratio of IC50 for human recombinant HDAC8 to IC50 for human recombinant HDAC6 | Homo sapiens | 22 | assay format | Scientific Literature | ||
| 16. | ALA2427135 | B | Inhibition of human recombinant HDAC11 expressed in baculovirus/sf9 cells using RHKKAc as substrate | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 17. | ALA2427136 | B | Inhibition of human recombinant HDAC6 expressed in baculovirus/sf9 cells using RHKKAc as substrate | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 18. | ALA2427138 | B | Inhibition of human recombinant HDAC8 expressed in baculovirus/sf9 cells using RHKAcKAc as substrate | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 19. | ALA2427139 | B | Inhibition of human recombinant HDAC1 expressed in baculovirus/sf9 cells using RHKKAc as substrate | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 20. | ALA2427283 | B | Inhibition of human recombinant HDAC2 expressed in baculovirus/sf9 cells using RHKKAc as substrate | Homo sapiens | 22 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!