| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2427289 | A | Half life in human liver microsomes at 1 uM | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 2. | ALA2427290 | A | Intrinsic clearance in human liver microsomes measured per mg of protein at 1 uM by LC-MS/MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 3. | ALA2427291 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 1 uM after 60 mins by LC-MS/MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 4. | ALA2427292 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 1 uM after 30 mins by LC-MS/MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 5. | ALA2427293 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 1 uM after 20 mins by LC-MS/MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 6. | ALA2427294 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 1 uM after 10 mins by LC-MS/MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 7. | ALA2427295 | A | Efflux ratio of apparent permeability across apical to basolateral side over basolateral to apical side in dog MDCK cells expressing MDR1 at 5 uM after 120 mins by LC-MS/MS analysis | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA2427296 | A | Permeability across basolateral to apical side in dog MDCK cells expressing MDR1 assessed as compound recovery at 5 uM after 120 mins by LC-MS/MS analysis | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA2427297 | A | Apparent permeability across basolateral to apical side in dog MDCK cells expressing MDR1 at 5 uM after 120 mins by LC-MS/MS analysis | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA2427298 | A | Permeability across apical to basolateral side in dog MDCK cells expressing MDR1 assessed as compound recovery at 5 uM after 120 mins by LC-MS/MS analysis | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA2427299 | A | Apparent permeability across apical to basolateral side in dog MDCK cells expressing MDR1 at 5 uM after 120 mins by LC-MS/MS analysis | Canis lupus familiaris | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA2427300 | A | Metabolic stability in mouse plasma after 2 hrs | Mus musculus | 3 | cell-free format | Scientific Literature | ||
| 13. | ALA2427301 | P | Aqueous solubility in DMSO buffer by nephelometric analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 14. | ALA2427302 | A | Metabolic stability in human plasma after 2 hrs | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
| 15. | ALA2427303 | A | Metabolic stability in rat plasma after 2 hrs | Rattus norvegicus | 3 | cell-free format | Scientific Literature | ||
| 16. | ALA2427306 | B | Inhibition of kappa-type opioid receptor (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 17. | ALA2427307 | B | Inhibition of histamine H2 receptor (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA2427308 | B | Inhibition of 5HT6 receptor (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 19. | ALA2427309 | B | Inhibition of rat purinergic receptor P2X subunit-2 expressed in Xenopus laevis oocytes assessed as inhibition of ATP-induced current at 3 uM by two-electrode voltage clamp method | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA2427310 | B | Inhibition of human purinergic receptor P2X subunit-2 expressed in Xenopus laevis oocytes assessed as inhibition of ATP-induced current at 3 uM by two-electrode voltage clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature |
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