# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2428101 | F | Increase of sister chromatid exchange in human BLM-deficient PSNG13 cells at 1 to 5 uM | Homo sapiens | 1 | ALA2424634 | assay format | Scientific Literature | |
2. | ALA2428102 | B | Inhibition of BLM in human PSNF5 cells assessed as increase of sister chromatid exchange at 1 to 5 uM | Homo sapiens | 1 | ALA2424634 | cell-based format | Scientific Literature | |
3. | ALA2428103 | B | Displacement of TAMRA-labeled oligonucleotide from BLM (unknown origin) | Homo sapiens | 1 | ALA2424634 | single protein format | Scientific Literature | |
4. | ALA2428104 | B | Inhibition of BLM (unknown origin) binding to single-stranded DNA by fluorescence polarization analysis | Homo sapiens | 1 | ALA2424634 | single protein format | Scientific Literature | |
5. | ALA2428105 | B | Competitive inhibition of BLM (unknown origin) using ATP by Lineweaver-Burk double reciprocal plot analysis | Homo sapiens | 1 | ALA2424634 | single protein format | Scientific Literature | |
6. | ALA2428106 | A | Apparent permeability from apical to basolateral side of human Caco2 cells | Homo sapiens | 2 | ALA2424634 | cell-based format | Scientific Literature | |
7. | ALA2428254 | A | Efflux ratio of permeability from apical to basolateral side over basolateral to apical side in human Caco2 cells | Homo sapiens | 2 | ALA2424634 | cell-based format | Scientific Literature | |
8. | ALA2428255 | A | Half life in mouse liver microsomes in presence of NADPH | Mus musculus | 2 | ALA2424634 | microsome format | Scientific Literature | |
9. | ALA2428256 | A | Metabolic stability of the compound in mouse plasma assessed as compound remaining after 5 hrs | Mus musculus | 2 | ALA2424634 | cell-free format | Scientific Literature | |
10. | ALA2428257 | P | Kinetic solubility of the compound in PBS buffer at pH 7.4 | 2 | ALA2424634 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA2428258 | B | Selectivity ratio of IC50 for WRN (unknown origin) to IC50 for BLM (unknown origin) | Homo sapiens | 9 | ALA2424634 | assay format | Scientific Literature | |
12. | ALA2428259 | B | Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assay | Homo sapiens | 9 | ALA2424634 | single protein format | Scientific Literature | |
13. | ALA2428260 | B | Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay | Homo sapiens | 9 | ALA2424634 | single protein format | Scientific Literature | |
14. | ALA2428261 | B | Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay | Homo sapiens | 57 | ALA2424634 | single protein format | Scientific Literature | |
15. | ALA3214945 | F | PubChem BioAssay. qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (3D7) proliferation. (Class of assay: confirmatory) | 940 | ALA1201862 | assay format | PubChem BioAssays | ||
16. | ALA3215001 | F | PubChem BioAssay. qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation. (Class of assay: confirmatory) | 1,150 | ALA1201862 | assay format | PubChem BioAssays | ||
17. | ALA3214813 | F | PubChem BioAssay. qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (DD2) proliferation (Rep 2). (Class of assay: confirmatory) | 1,069 | ALA1201862 | assay format | PubChem BioAssays | ||
18. | ALA3214842 | F | PubChem BioAssay. qHTS profiling of the MIPE4 collection as inhibitors of Plasmodium falciparum (HB3) proliferation. (Class of assay: confirmatory) | 881 | ALA1201862 | assay format | PubChem BioAssays |