# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2427705 | P | Half life in phosphate buffer at pH 7.4 at 50 uM by LC-MS analysis in presence of glutathione | 44 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA2427707 | P | Lipophilicity, log D of the compound at pH 7.4 | 13 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA2427712 | B | Selectivity ratio of IC50 for wild type EGFR phosphorylation in human LoVo cells over IC50 for EGFR L858R/T970M double mutant phosphorylation in human NCI-H1975 cells | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
4. | ALA2427713 | B | Inhibition of wild type EGFR phosphorylation in human LoVo cells after 2 hrs by fluorescence assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
5. | ALA2427714 | B | Inhibition of EGFR exon 19 deletion activating mutant phosphorylation in human PC9 cells after 2 hrs by fluorescence assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
6. | ALA2427158 | B | Inhibition of EGFR L858R/T970M double mutant phosphorylation in human NCI-H1975 cells after 2 hrs by fluorescence assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
7. | ALA3389020 | B | Inhibition of EGFR L858R/T970M double mutant phosphorylation in human NCI-H1975 cells after 2 hrs by fluorescence assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
8. | ALA3389021 | B | Inhibition of EGFR exon 19 deletion activating mutant phosphorylation in human PC9 cells after 2 hrs by fluorescence assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
9. | ALA3389022 | B | Inhibition of wild type EGFR phosphorylation in human LoVo cells after 2 hrs by fluorescence assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
10. | ALA3389023 | P | Lipophilicity, log D of the compound at pH 7.4 | 19 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA3389024 | A | Cmax in nude mouse at 50 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
12. | ALA3389025 | A | AUC in nude mouse at 50 mg/kg, po | Mus musculus | 3 | organism-based format | Scientific Literature | ||
13. | ALA3389027 | P | Thermodynamic solubility of the compound at pH 7.4 | 13 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA3389028 | B | Inhibition of human ERG | Homo sapiens | 13 | single protein format | Scientific Literature | ||
15. | ALA3389029 | B | Inhibition of IGF1R (unknown origin) | Homo sapiens | 13 | single protein format | Scientific Literature | ||
16. | ALA3389031 | B | Inhibition of CAMKKbeta (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
17. | ALA3389032 | B | Inhibition of IGF1R (unknown origin) at 1 uM relative to control | Homo sapiens | 5 | single protein format | Scientific Literature |