# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2427110 | A | Cytotoxicity against rat L6 cells assessed as growth inhibition after 72 hrs by fluorometric analysis | Rattus norvegicus | 14 | cell-based format | Scientific Literature | ||
2. | ALA2427111 | T | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for chloroquine/pyrimethamine-resistant Plasmodium falciparum K1 | 13 | cell-based format | Scientific Literature | |||
3. | ALA2427112 | F | Antiplasmodial activity against chloroquine/pyrimethamine-resistant Plasmodium falciparum K1 assessed as growth inhibition after 24 hrs by [3H]-hypoxanthine incorporation assay | Plasmodium falciparum | 15 | organism-based format | Scientific Literature | ||
4. | ALA2427113 | B | Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 mins | Plasmodium falciparum | 14 | single protein format | Scientific Literature | ||
5. | ALA2427114 | B | Inhibition of recombinant Plasmodium falciparum 3D7 FabG using acetoacetyl-CoA as substrate after 10 mins in presence of NADPH | Plasmodium falciparum 3D7 | 14 | single protein format | Scientific Literature | ||
6. | ALA2427115 | B | Inhibition of recombinant Plasmodium falciparum FabI using crotonoyl-CoA as substrate assessed as consumption of NADH after 10 mins | Plasmodium falciparum | 14 | assay format | Scientific Literature |