# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2426817 | ADME | Metabolic stability in human liver microsomes assessed as compound remaining at 1 uM after 15 mins | Homo sapiens | 2 | ALA2424640 | microsome format | Scientific Literature | |
2. | ALA2426818 | ADME | Metabolic stability in rat liver microsomes assessed as compound remaining at 1 uM after 15 mins | Rattus norvegicus | 2 | ALA2424640 | microsome format | Scientific Literature | |
3. | ALA2426819 | Functional | Positive allosteric modulation of human mGlu8 receptor expressed in HEK293 cells by fluorescent Ca2+ assay | Homo sapiens | 5 | ALA2424640 | cell-based format | Scientific Literature | |
4. | ALA2426820 | Functional | Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells by fluorescent Ca2+ assay | Homo sapiens | 4 | ALA2424640 | cell-based format | Scientific Literature | |
5. | ALA2426821 | Functional | Positive allosteric modulation of rat mGlu6 receptor expressed in CHO cells by [35S]-GTPgammaS binding assay | Rattus norvegicus | 4 | ALA2424640 | cell-based format | Scientific Literature | |
6. | ALA2426822 | Functional | Positive allosteric modulation of human mGlu3 receptor expressed in HEK293 cells by fluorescent Ca2+ assay | Homo sapiens | 4 | ALA2424640 | cell-based format | Scientific Literature | |
7. | ALA2426823 | Functional | Positive allosteric modulation of human mGlu4 receptor expressed in HEK293 cells by fluorescent Ca2+ assay | Homo sapiens | 4 | ALA2424640 | cell-based format | Scientific Literature | |
8. | ALA2426824 | Functional | Positive allosteric modulation of human mGlu2 receptor expressed in HEK293 cells by fluorescent Ca2+ assay | Homo sapiens | 5 | ALA2424640 | cell-based format | Scientific Literature | |
9. | ALA2426825 | Functional | Positive allosteric modulation of human mGlu1 receptor expressed in HEK293 cells by fluorescent Ca2+ assay | Homo sapiens | 5 | ALA2424640 | cell-based format | Scientific Literature | |
10. | ALA2426826 | Physicochemical | Kinetic solubility in aqueous buffer at pH 7.4 | 4 | ALA2424640 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA2426829 | Functional | Positive allosteric modulation of human mGluR5a transfected in HEK293 cells by calcium mobilization assay relative to glutamate | Homo sapiens | 29 | ALA2424640 | cell-based format | Scientific Literature | |
12. | ALA2426830 | Functional | Positive allosteric modulation of human mGluR5a transfected in HEK293 cells by calcium mobilization assay | Homo sapiens | 31 | ALA2424640 | cell-based format | Scientific Literature |