# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2434758 | B | Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after 120 mins by liquid scintillation counting | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
2. | ALA2434759 | F | Antidiabetic activity in Sprague-Dawley rat assessed as urinary glucose excretion at 30 mg/kg, po measured over 24 hrs | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
3. | ALA2434761 | A | Half life in Sprague-Dawley rat at 3 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
4. | ALA2434762 | A | AUC (0 to infinity) in Sprague-Dawley rat at 3 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
5. | ALA2434763 | A | Total clearance in Sprague-Dawley rat at 3 ug/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
6. | ALA2434764 | A | Volume of distribution at steady state in Sprague-Dawley rat at 3 ug/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
7. | ALA2432341 | A | Half life in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
8. | ALA2432342 | A | Tmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
9. | ALA2432343 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
10. | ALA2432344 | A | AUC (0 to infinity) in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
11. | ALA2432345 | A | Oral bioavailability in Sprague-Dawley rat at 10 mg/kg | Rattus norvegicus | 2 | organism-based format | Scientific Literature |