# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2432165 | Binding | Inhibition of Pyk2 (unknown origin) | Homo sapiens | 1 | ALA2429754 | single protein format | Scientific Literature | |
2. | ALA2432166 | Binding | Reversible inhibition of FAK kinase domain (amino acid 410-689) (unknown origin) assessed as inhibition of Phosphorylation of p(Glu/Tyr) by spectrophotometry | Homo sapiens | 1 | ALA2429754 | single protein format | Scientific Literature | |
3. | ALA4303805 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
4. | ALA4326592 | Functional | Antiproliferative activity against human A549 cells after 2 days by spectrophotometric analysis | Homo sapiens | 24 | ALA4325842 | cell-based format | Scientific Literature | |
5. | ALA4326593 | Functional | Antiproliferative activity against human U87MG cells after 2 days by spectrophotometric analysis | Homo sapiens | 24 | ALA4325842 | cell-based format | Scientific Literature | |
6. | ALA4326594 | Functional | Antiproliferative activity against human HeLa cells after 2 days by spectrophotometric analysis | Homo sapiens | 24 | ALA4325842 | cell-based format | Scientific Literature | |
7. | ALA4326595 | Functional | Antiproliferative activity against human OVCAR3 cells after 2 days by spectrophotometric analysis | Homo sapiens | 24 | ALA4325842 | cell-based format | Scientific Literature | |
8. | ALA4326596 | Functional | Antiproliferative activity against human HepG2 cells after 2 days by spectrophotometric analysis | Homo sapiens | 24 | ALA4325842 | cell-based format | Scientific Literature | |
9. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
10. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
11. | ALA4730726 | Binding | Protac activity at CRBN/FAK in human PA1 cells assessed as FAK degradation at 10 uM after 8 hrs | Homo sapiens | 2 | ALA4725428 | cell-based format | Scientific Literature | |
12. | ALA4730735 | Binding | Protac activity at CRBN/FAK in mouse TM3 cells assessed as reduction in FAK autophosphorylation at tyr 397 residue at 3 uM after 8 hrs by Western blot analysis | Mus musculus | 1 | ALA4725428 | cell-based format | Scientific Literature |