# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2434809 | B | Inhibition of influenza A virus HA-tagged polymerase acidic protien transfected in HEK293T cells after 24 hrs by ELISA | Influenza A virus | 27 | ALA2429796 | cell-based format | Scientific Literature | |
2. | ALA2434810 | A | Cytotoxicity against MDCK cells | Canis lupus familiaris | 18 | ALA2429796 | cell-based format | Scientific Literature | |
3. | ALA2434811 | F | Antiviral activity against Influenza A virus A/WSN/33(H1N1) infected in MDCK cells after 48 hrs by plaque reduction assay | Influenza A virus | 27 | ALA2429796 | organism-based format | Scientific Literature | |
4. | ALA4007862 | B | Inhibition of recombinant human IDO1 expressed in bacterial expression system using L-Tryptophan as substrate after 25 mins in absence of GSH and presence of tween20 by fluorescence assay | Homo sapiens | 57 | ALA4007389 | assay format | Scientific Literature | |
5. | ALA4007866 | B | Inhibition of recombinant human IDO1 S167A mutant expressed in Escherichia coli SG13009(pREP4) using L-Tryptophan as substrate after 25 mins by fluorescence assay | Homo sapiens | 66 | ALA4007389 | assay format | Scientific Literature | |
6. | ALA4007867 | B | Selectivity ratio of IC50 for recombinant human IDO1 S167A mutant expressed in Escherichia coli SG13009(pREP4) to IC50 for recombinant human IDO1 expressed in bacterial expression system | Homo sapiens | 47 | ALA4007389 | assay format | Scientific Literature | |
7. | ALA4007890 | B | Inhibition of full length recombinant human His-tagged IDO1 expressed in mouse LLTC cells using L-tryptophan as substrate after 24 hrs | Homo sapiens | 58 | ALA4007389 | cell-based format | Scientific Literature | |
8. | ALA4007891 | A | Cytotoxicity against mouse LLTC cells assessed as reduction in cell viability after 24 hrs by MTT assay | Mus musculus | 60 | ALA4007389 | cell-based format | Scientific Literature | |
9. | ALA4483863 | F | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent inhibition of light emission compared to control. (Single Point Inhibition, %) | Plasmodium berghei | 9,989 | ALA4483862 | organism-based format | Winzeler Lab Plasmodium Screening Data | |
10. | ALA4483864 | F | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent inhibition of light emission compared to control. (Single Point Inhibition, %) | Homo sapiens | 9,989 | ALA4483862 | cell-based format | Winzeler Lab Plasmodium Screening Data | |
11. | ALA5236849 | F | Antiviral activity against influenza A H1N1 | Influenza A virus | 4 | ALA5236544 | organism-based format | Scientific Literature | |
12. | ALA5236850 | F | Antiviral activity against RSV | Respiratory syncytial virus | 3 | ALA5236544 | organism-based format | Scientific Literature |