# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2432232 | A | Cytotoxicity against human MCF7-neo/Her2 cells assessed as cell viability at 50 uM by Sytox Green/Hoescht 33342 staining assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA2432233 | B | Inhibition of LDHA in human MCF7-neo/HER2 cells assessed as inhibition of lactate production at 50 uM after 6 hrs by spectrophotometric analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA2432234 | A | Oral bioavailability in Sprague-Dawley rat at 1.5 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
4. | ALA2432235 | A | Half life in Sprague-Dawley rat at 1.5 mg/kg, po and 0.5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
5. | ALA2432236 | A | AUC (infinity) in Sprague-Dawley rat at 1.5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
6. | ALA2432237 | A | Cmax in Sprague-Dawley rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
7. | ALA2432238 | A | Volume of distribution in Sprague-Dawley rat at 1.5 mg/kg, po and 0.5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA2432239 | A | Plasma clearance in Sprague-Dawley rat at 1.5 mg/kg, po and 0.5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA2432240 | A | Inhibition of CYP2C19 (unknown origin) up to 10 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
10. | ALA2432241 | A | Inhibition of CYP1A2 (unknown origin) up to 10 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
11. | ALA2432242 | A | Inhibition of CYP2D6 (unknown origin) up to 10 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
12. | ALA2432243 | A | Inhibition of CYP2C9 (unknown origin) up to 10 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
13. | ALA2432244 | P | Aqueous kinetic solubility of the compound at pH 7.4 | 2 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA2432245 | A | Inhibition of CYP3A4 (unknown origin) up to 10 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
15. | ALA2432246 | A | Permeability across basolateral to apical side in MDCK cells | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
16. | ALA2432247 | A | Plasma protein binding in rat at 5 uM after 4 hrs by equilibrium dialysis method | Rattus norvegicus | 2 | cell-free format | Scientific Literature | ||
17. | ALA2432248 | A | Permeability across apical to basolateral side in MDCK cells | Canis lupus familiaris | 2 | cell-based format | Scientific Literature | ||
18. | ALA2432249 | A | Plasma protein binding in human at 5 uM after 4 hrs by equilibrium dialysis method | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
19. | ALA2432250 | A | Clearance in rat liver microsomes at 1 uM | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
20. | ALA2432251 | A | Clearance in human liver microsomes at 1 uM | Homo sapiens | 2 | microsome format | Scientific Literature |