# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2434348 | B | Binding affinity to transthyretin tetrameric form (unknown origin) assessed as inhibition of protein dissociation to monomeric or dimeric form at 100 uM by size exclusion chromatographic analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA2434349 | B | Displacement of anilinonaphthalene-1-sulfonate from transthyretin thyroxin binding site (unknown origin) up to 135 uM after 20 mins by fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA2434350 | B | Displacement of anilinonaphthalene-1-sulfonate from transthyretin thyroxin binding site (unknown origin) at 13.5 uM after 20 mins by fluorescence assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
4. | ALA2434351 | B | Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation at 10 mol equiv measured at 12 hrs by thioflavin T-based fluorescence assay relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
5. | ALA2434352 | B | Inhibition of transthyretin (unknown origin) fibril formation at 2 mol equiv after 1 week by AFM spectroscopic analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA2434353 | B | Inhibition of transthyretin (unknown origin) fibril formation at 5 mol equiv after 1 week by AFM spectroscopic analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA2434354 | B | Inhibition of transthyretin (unknown origin) fibril formation at 20 to 10 mol equiv after 1 week by AFM spectroscopic analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA2434356 | B | Inhibition of transthyretin (unknown origin) aggregation at 20 mol equiv measured at 36 hrs by congo red assay relative to control | Homo sapiens | 2 | single protein format | Scientific Literature |