| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2432198 | A | Drug metabolism in monkey liver microsomes assessed as (4R,5S,6S)-3-((3S,5S)-5-(3-(ethoxycarbonyl)phenylcarbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid level after 15 mins in presence of NADPH | Macaca mulatta | 1 | microsome format | Scientific Literature | ||
| 2. | ALA2432199 | A | Drug metabolism in dog liver microsomes assessed as (4R,5S,6S)-3-((3S,5S)-5-(3-(ethoxycarbonyl)phenylcarbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid level after 15 mins in presence of NADPH | Canis lupus familiaris | 1 | microsome format | Scientific Literature | ||
| 3. | ALA2432200 | A | Drug metabolism in human liver microsomes assessed as (4R,5S,6S)-3-((3S,5S)-5-(3-(ethoxycarbonyl)phenylcarbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid level after 15 mins in presence of NADPH | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 4. | ALA2432201 | A | Drug metabolism in rat liver microsomes assessed as (4R,5S,6S)-3-((3S,5S)-5-(3-(ethoxycarbonyl)phenylcarbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid level after 15 mins in presence of NADPH | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 5. | ALA2432203 | A | Bioavailability in Beagle dog at 10 mg/kg, ID administered as infusion | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA2432204 | A | Bioavailability in Beagle dog assessed as ertapenem at 10 mg/kg, ID administered as infusion | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA2432205 | A | AUC (0 to 8 hrs) in Beagle dog assessed as (4R,5S,6S)-3-((3S,5S)-5-(3-(ethoxycarbonyl)phenylcarbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid at 10 mg/kg, ID administered as infusion | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
| 8. | ALA2432206 | A | AUC (0 to 8 hrs) in Beagle dog assessed as 3-((2S,4S)-4-((4R,5S,6S)-2-(ethoxycarbonyl)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-ylthio)pyrrolidine-2-carboxamido)benzoic acid at 10 mg/kg, ID administered as infusion | Canis lupus familiaris | 2 | organism-based format | Scientific Literature | ||
| 9. | ALA2432207 | A | AUC (0 to 8 hrs) in Beagle dog assessed as ertapenem at 10 mg/kg, ID administered as infusion | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA2432209 | A | AUC (0 to 8 hrs) in Beagle dog at 10 mg/kg, ID administered as infusion | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA2432210 | A | Bioavailability in Sprague-Dawley rat at 4.4 mg/kg, ID administered as infusion | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA2432211 | A | Bioavailability in Sprague-Dawley rat assessed as ertapenem at 4.4 mg/kg, ID administered as infusion | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA2432337 | A | AUC (0 to 8 hrs) in Sprague-Dawley rat assessed as (4R,5S,6S)-3-((3S,5S)-5-(3-(ethoxycarbonyl)phenylcarbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid at 4.4 mg/kg, ID administered as infusion | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA2432340 | A | AUC (0 to 8 hrs) in Sprague-Dawley rat assessed as 3-((2S,4S)-4-((4R,5S,6S)-2-(ethoxycarbonyl)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-ylthio)pyrrolidine-2-carboxamido)benzoic acid at 4.4 mg/kg, ID administered as infusion | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA2432508 | A | AUC (0 to 8 hrs) in Sprague-Dawley rat assessed as ertapenem at 4.4 mg/kg, ID administered as infusion | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA2432512 | A | AUC (0 to 8 hrs) in Sprague-Dawley rat at 4.4 mg/kg, ID administered as infusion | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA2432514 | A | Apparent permeability of the compound in pig LLC-PK1 cells | Sus scrofa | 4 | cell-based format | Scientific Literature | ||
| 18. | ALA2432629 | A | Drug metabolism in monkey hepatocytes assessed as 3-((2S,4S)-4-((4R,5S,6S)-2-(ethoxycarbonyl)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-ylthio)pyrrolidine-2-carboxamido)benzoic acid level after 60 mins | Macaca mulatta | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA2432630 | A | Drug metabolism in rat hepatocytes assessed as 3-((2S,4S)-4-((4R,5S,6S)-2-(ethoxycarbonyl)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-ylthio)pyrrolidine-2-carboxamido)benzoic acid level after 60 mins | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA2432631 | A | Drug metabolism in dog hepatocytes assessed as 3-((2S,4S)-4-((4R,5S,6S)-2-(ethoxycarbonyl)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-ylthio)pyrrolidine-2-carboxamido)benzoic acid level after 60 mins | Canis lupus familiaris | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!