# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2432203 | ADME | Bioavailability in Beagle dog at 10 mg/kg, ID administered as infusion | Canis lupus familiaris | 3 | ALA2429826 | organism-based format | Scientific Literature | |
2. | ALA2432204 | ADME | Bioavailability in Beagle dog assessed as ertapenem at 10 mg/kg, ID administered as infusion | Canis lupus familiaris | 3 | ALA2429826 | organism-based format | Scientific Literature | |
3. | ALA2432207 | ADME | AUC (0 to 8 hrs) in Beagle dog assessed as ertapenem at 10 mg/kg, ID administered as infusion | Canis lupus familiaris | 3 | ALA2429826 | organism-based format | Scientific Literature | |
4. | ALA2432209 | ADME | AUC (0 to 8 hrs) in Beagle dog at 10 mg/kg, ID administered as infusion | Canis lupus familiaris | 3 | ALA2429826 | organism-based format | Scientific Literature | |
5. | ALA2432649 | ADME | Prodrug conversion in monkey plasma assessed as ertapenem level at 50 uM after 60 mins by LC-MS/MS analysis | Macaca mulatta | 4 | ALA2429826 | cell-free format | Scientific Literature | |
6. | ALA2432650 | ADME | Metabolic stability in monkey plasma assessed as compound remaining at 50 uM after 60 mins by LC-MS/MS analysis | Macaca mulatta | 5 | ALA2429826 | cell-free format | Scientific Literature | |
7. | ALA2432651 | ADME | Prodrug conversion in dog plasma assessed as ertapenem level at 50 uM after 60 mins by LC-MS/MS analysis | Canis lupus familiaris | 4 | ALA2429826 | cell-free format | Scientific Literature | |
8. | ALA2432767 | ADME | Metabolic stability in dog plasma assessed as compound remaining at 50 uM after 60 mins by LC-MS/MS analysis | Canis lupus familiaris | 5 | ALA2429826 | cell-free format | Scientific Literature | |
9. | ALA2432768 | ADME | Prodrug conversion in human plasma assessed as ertapenem level at 50 uM after 60 mins by LC-MS/MS analysis | Homo sapiens | 4 | ALA2429826 | cell-free format | Scientific Literature | |
10. | ALA2432769 | ADME | Metabolic stability in human plasma assessed as compound remaining at 50 uM after 60 mins by LC-MS/MS analysis | Homo sapiens | 5 | ALA2429826 | cell-free format | Scientific Literature | |
11. | ALA2432770 | ADME | Prodrug conversion in rat plasma assessed as ertapenem level at 50 uM after 60 mins by LC-MS/MS analysis | Rattus norvegicus | 4 | ALA2429826 | cell-free format | Scientific Literature | |
12. | ALA2432771 | ADME | Metabolic stability in rat plasma assessed as compound remaining at 50 uM after 60 mins by LC-MS/MS analysis | Rattus norvegicus | 5 | ALA2429826 | cell-free format | Scientific Literature | |
13. | ALA2432772 | Physicochemical | Drug degradation in simulated gastric fluid assessed as beta-lactam ring open decomposition products level after 60 mins at pH 6.5 by by LC-MS/MS analysis | 4 | ALA2429826 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA2432773 | Physicochemical | Stability of the compound in FaSSIF after 3 hrs at pH 2 by LC-MS/MS analysis | 4 | ALA2429826 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA2432774 | Physicochemical | Chemical stability of the compound in phosphate buffer after 3 hrs at pH 7 by LC-MS/MS analysis | 4 | ALA2429826 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA3388193 | ADME | Stability in rat plasma assessed as compound remaining at 50 uM at 37 degC after 60 mins by LC-MS/MS method | Rattus norvegicus | 57 | ALA3351346 | cell-free format | Scientific Literature | |
17. | ALA3388194 | ADME | Drug metabolism in rat plasma assessed as conversion to ertapenem at 50 uM at 37 degC after 60 mins by LC-MS/MS method | Rattus norvegicus | 57 | ALA3351346 | cell-free format | Scientific Literature | |
18. | ALA3388195 | ADME | Stability in human plasma assessed as compound remaining at 50 uM at 37 degC after 60 mins by LC-MS/MS method | Homo sapiens | 57 | ALA3351346 | cell-free format | Scientific Literature | |
19. | ALA3388196 | ADME | Drug metabolism in human plasma assessed as conversion to ertapenem at 50 uM at 37 degC after 60 mins by LC-MS/MS method | Homo sapiens | 57 | ALA3351346 | cell-free format | Scientific Literature | |
20. | ALA3388197 | ADME | Stability in pH 2.0 simulated gastric fluid assessed as compound degradation to beta-lactam ring open products at 1 uM after 60 mins by LC-MS/MS method | 57 | ALA3351346 | tissue-based format | Scientific Literature |