# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2434084 | A | Intrinsic clearance in human hepatocytes measured per 10'6 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
2. | ALA2434085 | A | Intrinsic clearance in rat hepatocytes measured per 10'6 cells | Rattus norvegicus | 11 | cell-based format | Scientific Literature | ||
3. | ALA2434087 | F | Antiviral activity against Hepatitis C virus isolate Con1 infected in human 2209-23 cells after 72 hrs by luciferase reporter gene assay in presence of 40% human serum | Hepacivirus hominis | 15 | organism-based format | Scientific Literature | ||
4. | ALA2434095 | A | Clearance in Wistar/Han rat at 0.5 mg/kg, iv administered as bolus dose | Rattus norvegicus | 12 | organism-based format | Scientific Literature | ||
5. | ALA2434096 | A | Intrinsic clearance in rat liver microsomes assessed per mg of protein preincubated for 2 mins followed by NADPH addition measured after 30 mins by RP-HPLC/UV/MS analysis | Rattus norvegicus | 15 | microsome format | Scientific Literature | ||
6. | ALA2434098 | A | Intrinsic clearance in human liver microsomes assessed per mg of protein at 20 uM preincubated for 2 mins followed by NADPH addition measured after 30 mins by RP-HPLC/UV/MS analysis | Homo sapiens | 15 | microsome format | Scientific Literature | ||
7. | ALA2434101 | F | Antiviral activity against Hepatitis C virus isolate Con1 infected in human 2209-23 cells after 72 hrs by luciferase reporter gene assay | Hepacivirus hominis | 25 | organism-based format | Scientific Literature | ||
8. | ALA2434102 | F | Antiviral activity against Hepatitis C virus isolate H77 infected in human 2209-23 cells after 72 hrs by luciferase reporter gene assay | Hepacivirus hominis | 25 | organism-based format | Scientific Literature | ||
9. | ALA2434103 | B | Inhibition of N-terminal 6-his tagged HCV isolate Con1 NS5B5 polymerase containing 21-amino acid deletion at C-terminus expressed in Escherichia coli using radiolabeled UTP as substrate after 2 hrs by scintillation counting analysis | Hepatitis C virus | 26 | organism-based format | Scientific Literature |