# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2432678 | A | Reversible inhibition of CYP3A4 in human liver microsomes assessed as inhibition of midazolam turnover preincubated for 3 mins followed by midazolam and NADPH addition measured after 5 mins by HPLC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
2. | ALA2432679 | F | Ratio of EC50 for Hepatitis C virus RO-38 expressing NS5B S556G mutant to EC50 for Hepatitis C virus H77 expressing NS5B | Hepacivirus hominis | 1 | organism-based format | Scientific Literature | ||
3. | ALA2432680 | F | Antiviral activity against Hepatitis C virus 1b RO-10 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
4. | ALA2432681 | F | Antiviral activity against Hepatitis C virus 1b RO-9 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
5. | ALA2432682 | F | Antiviral activity against Hepatitis C virus 1b RO-8 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
6. | ALA2432683 | F | Antiviral activity against Hepatitis C virus 1b RO-7 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
7. | ALA2432684 | F | Antiviral activity against Hepatitis C virus 1b RO-4 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
8. | ALA2432685 | F | Antiviral activity against Hepatitis C virus 1b RO-3 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
9. | ALA2432686 | F | Antiviral activity against Hepatitis C virus 1b RO-2 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
10. | ALA2432687 | F | Antiviral activity against Hepatitis C virus 1b RO-1 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
11. | ALA2432688 | F | Antiviral activity against Hepatitis C virus Con1 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
12. | ALA2432689 | F | Antiviral activity against Hepatitis C virus 1a RO-41 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
13. | ALA2432803 | F | Antiviral activity against Hepatitis C virus 1a RO-38 expressing NS5B S556G mutant assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
14. | ALA2432804 | F | Antiviral activity against Hepatitis C virus 1a RO-35 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
15. | ALA2432805 | F | Antiviral activity against Hepatitis C virus 1a RO-34 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
16. | ALA2432806 | F | Antiviral activity against Hepatitis C virus 1a RO-33 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
17. | ALA2432807 | F | Antiviral activity against Hepatitis C virus 1a RO-32 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
18. | ALA2432808 | F | Antiviral activity against Hepatitis C virus 1a RO-28 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
19. | ALA2432809 | F | Antiviral activity against Hepatitis C virus 1a RO-24 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature | ||
20. | ALA2432810 | F | Antiviral activity against Hepatitis C virus 1a RO-22 expressing NS5B assessed as inhibition of viral replication after 4 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | organism-based format | Scientific Literature |