# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2434287 | A | Half life in rat liver microsomes at 1 uM by LC-MS/MS analysis | Rattus norvegicus | 56 | microsome format | Scientific Literature | ||
2. | ALA2434292 | A | Inhibition of CYP3A4 in human liver microsomes assessed as midazolam hydroxylation to 1'-hydroxymidazolam at 1 uM after 10 mins relative to control | Homo sapiens | 33 | microsome format | Scientific Literature | ||
3. | ALA2434294 | A | Inhibition of CYP2D6 in human liver microsomes assessed as bufuralol hydroxylation to 4'-hydroxybufuralol at 1 uM after 10 mins relative to control | Homo sapiens | 33 | microsome format | Scientific Literature | ||
4. | ALA2434295 | A | Inhibition of CYP1A2 in human liver microsomes assessed as phenacetin demethylation to acetaminophen at 1 uM after 10 mins relative to control | Homo sapiens | 33 | microsome format | Scientific Literature | ||
5. | ALA2432690 | A | Inhibition of CYP2C9 in human liver microsomes assessed as tolbutamide hydroxylation to hydroxytolbutamide at 1 uM after 10 mins relative to control | Homo sapiens | 33 | microsome format | Scientific Literature | ||
6. | ALA2432692 | F | Antichagasic activity against amastigote stage of Trypanosoma cruzi infected in human myoblasts assessed as intracellular parasite growth inhibition after 72 hrs by DAPI staining assay | Trypanosoma cruzi | 52 | organism-based format | Scientific Literature | ||
7. | ALA2432693 | A | Half life in human liver microsomes at 1 uM by LC-MS/MS analysis | Homo sapiens | 59 | microsome format | Scientific Literature | ||
8. | ALA2432694 | A | Half life in mouse liver microsomes at 1 uM by LC-MS/MS analysis | Mus musculus | 59 | microsome format | Scientific Literature | ||
9. | ALA2432695 | B | Binding affinity to recombinant Trypanosoma cruzi CYP51 expressed in Escherichia coli by UV-Vis spectrophotometric analysis | Trypanosoma cruzi | 56 | assay format | Scientific Literature |