# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2438187 | A | Oral bioavailability in C57BL/6 mouse blood at 3 mg/kg | Mus musculus | 2 | organism-based format | Scientific Literature | ||
2. | ALA2438193 | A | Ratio of drug level in brain to blood in C57BL/6 mouse at 3 mg/kg, po after 15 mins | Mus musculus | 2 | organism-based format | Scientific Literature | ||
3. | ALA2438194 | A | AUC (infinity) in C57BL/6 mouse blood at 3 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
4. | ALA2438195 | A | Cmax in C57BL/6 mouse blood at 3 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
5. | ALA2438196 | A | Total blood clearance in C57BL/6 mouse at 1 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
6. | ALA2438197 | A | Volume of distribution at steady state in C57BL/6 mouse at 1 mg/kg, iv | Mus musculus | 2 | organism-based format | Scientific Literature | ||
7. | ALA2438198 | F | Antagonist activity at human OX2 receptor expressed in HEK cells assessed as inhibition of orexin A-induced Ca2+ accumulation after 1 hr by Fluo-4-AM staining-based FLIPR assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
8. | ALA2438199 | F | Antagonist activity at human OX1 receptor expressed in CHO cells assessed as inhibition of orexin A-induced Ca2+ accumulation after 1 hr by Fluo-4-AM staining-based FLIPR assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
9. | ALA3705337 | B | Radioligand Binding Assay : Radioligand binding assay using orexin receptor. | Homo sapiens | 66 | single protein format | BindingDB Database | ||
10. | ALA3705338 | B | FLIPR Assay : FLIPR assay using orexin receptor. | Homo sapiens | 125 | single protein format | BindingDB Database | ||
11. | ALA3707667 | B | Radioligand Binding Assay : Radioligand binding assay using orexin receptor. | Homo sapiens | 65 | single protein format | BindingDB Database | ||
12. | ALA3707782 | B | FLIPR Assay : FLIPR assay using orexin receptor. | Homo sapiens | 148 | single protein format | BindingDB Database |