| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2439562 | A | Half life in Sprague-Dawley rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA2439563 | A | Clearance in Sprague-Dawley rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2439564 | A | MRT (0 to infinity) in Sprague-Dawley rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA2439565 | A | MRT (0 to t) in Sprague-Dawley rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA2439566 | A | AUC (0 to infinity) in Sprague-Dawley rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA2439567 | A | AUC (0 to t) in Sprague-Dawley rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA2439568 | A | Cmax in Sprague-Dawley rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA2439569 | A | Tmax in Sprague-Dawley rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA2439680 | F | Agonist activity at mouse TGR5 expressed in HEK293 cells assessed CRE-induced luciferase activity after 5.5 hrs by reporter gene assay relative to control | Mus musculus | 14 | cell-based format | Scientific Literature | ||
| 10. | ALA2439681 | F | Agonist activity at mouse TGR5 expressed in HEK293 cells assessed CRE-induced luciferase activity after 5.5 hrs by reporter gene assay | Mus musculus | 14 | cell-based format | Scientific Literature | ||
| 11. | ALA2439682 | F | Antidiabetic activity in oral glucose loaded ICR mouse assessed as reduction of blood glucose AUC (0 to 120 mins) at 50 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA2439683 | T | Toxicity in oral glucose loaded ICR mouse assessed as effect on size of the gallbladder at 50 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA2439684 | F | Agonist activity at human TGR5 expressed in HEK293 cells assessed CRE-induced luciferase activity after 5.5 hrs by reporter gene assay relative to control | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 14. | ALA2439686 | F | Agonist activity at human TGR5 expressed in HEK293 cells assessed CRE-induced luciferase activity after 5.5 hrs by reporter gene assay | Homo sapiens | 31 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!