# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2437628 | F | Ex vivo receptor occupancy of histamine H3 receptor in mouse brain after 72 hrs by time-course method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
2. | ALA2437978 | F | Antiobesity activity in diet-induced obesity mouse model assessed as reduction in body weight at 10 mg/kg, po after 4 days relative to vehicle-treated control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
3. | ALA2437979 | F | Antiobesity activity in diet-induced obesity mouse model assessed as reduction in body weight at 3 mg/kg, po after 4 days relative to vehicle-treated control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
4. | ALA2437980 | F | Antiobesity activity in diet-induced obesity mouse model assessed as reduction in body weight at 1 mg/kg, po after 4 days relative to vehicle-treated control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
5. | ALA2437981 | A | Drug uptake in rat brain at 100 mg/kg, po after 4 hrs by Irwin test | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
6. | ALA2437982 | A | Drug uptake in rat brain at 300 mg/kg, po after 4 hrs by Irwin test | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
7. | ALA2437983 | A | Plasma concentration in rat at 300 mg/kg, po after 4 hrs by Irwin test | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA2437984 | T | Toxicity in rat assessed as behavioral change at 100 to 300 mg/kg, po by Irwin test | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA2437985 | A | Plasma concentration in rat at 100 mg/kg, po after 4 hrs by Irwin test | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
10. | ALA2437986 | A | Inhibition of CYP2C9 in human liver microsomes | Homo sapiens | 17 | microsome format | Scientific Literature | ||
11. | ALA2437987 | B | Inhibition of human ERG channel at 5 ug/ml after 30 mins by rubidium efflux assay | Homo sapiens | 17 | single protein format | Scientific Literature | ||
12. | ALA2437988 | A | Inhibition of CYP2D6 in human liver microsomes | Homo sapiens | 17 | microsome format | Scientific Literature | ||
13. | ALA2437989 | A | Inhibition of CYP3A4 in human liver microsomes | Homo sapiens | 17 | microsome format | Scientific Literature | ||
14. | ALA2437991 | F | Ex vivo displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in mouse cortex at 10 mg/kg, po after 4 hrs by topcount scintillation counting analysis | Mus musculus | 12 | organism-based format | Scientific Literature | ||
15. | ALA2437993 | B | Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor after 30 mins by scintillation counting analysis | Mus musculus | 18 | single protein format | Scientific Literature | ||
16. | ALA2437994 | B | Displacement of [3H]N-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK cells after 30 mins by scintillation counting analysis | Homo sapiens | 18 | cell-based format | Scientific Literature |