# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2437695 | A | Cmax in C57BL/6 mouse at 10 mg/kg, iv | Mus musculus | 6 | ALA2434948 | organism-based format | Scientific Literature | |
2. | ALA2437696 | A | AUC in C57BL/6 mouse brain at 10 mg/kg, iv | Mus musculus | 6 | ALA2434948 | organism-based format | Scientific Literature | |
3. | ALA2437697 | A | Apparent clearance in C57BL/6 mouse at 10 mg/kg, iv | Mus musculus | 6 | ALA2434948 | organism-based format | Scientific Literature | |
4. | ALA2437698 | A | Apparent volume of distribution during terminal phase in C57BL/6 mouse at 10 mg/kg, iv | Mus musculus | 6 | ALA2434948 | organism-based format | Scientific Literature | |
5. | ALA2437699 | A | Half life in C57BL/6 mouse at 10 mg/kg, iv | Mus musculus | 6 | ALA2434948 | organism-based format | Scientific Literature | |
6. | ALA2437700 | A | AUC in C57BL/6 mouse at 10 mg/kg, iv | Mus musculus | 6 | ALA2434948 | organism-based format | Scientific Literature | |
7. | ALA2437701 | A | Plasma protein binding in human at 10 uM after 6 hrs by equilibrium dialysis method | Homo sapiens | 7 | ALA2434948 | cell-free format | Scientific Literature | |
8. | ALA2437702 | B | Inhibition of MLK3 in mouse BV2 cells assessed as inhibition of LPS-induced TNFalpha release after 8 hrs by ELISA | Mus musculus | 8 | ALA2434948 | cell-based format | Scientific Literature | |
9. | ALA2437703 | B | Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATP | Homo sapiens | 8 | ALA2434948 | single protein format | Scientific Literature | |
10. | ALA2438981 | B | Inhibition of wild type human FLT3 at 1 umol by high throughput ATP-[33P] radiolabeled assay relative to control | Homo sapiens | 6 | ALA2434948 | single protein format | Scientific Literature | |
11. | ALA2439119 | B | Inhibition of human wild type LRRK2 by qPCR analysis | Homo sapiens | 8 | ALA2434948 | single protein format | Scientific Literature | |
12. | ALA2439898 | A | Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of dextromethorphan metabolism by HPLC/MS analysis | Homo sapiens | 6 | ALA2434948 | microsome format | Scientific Literature | |
13. | ALA2439899 | A | Inhibition of CYP2C9 in human liver microsomes assessed as inhibition of midazolam metabolism by HPLC/MS analysis | Homo sapiens | 6 | ALA2434948 | microsome format | Scientific Literature | |
14. | ALA2439900 | A | Inhibition of CYP2D6 in human liver microsomes assessed as inhibition of diclofenac metabolism by HPLC/MS analysis | Homo sapiens | 6 | ALA2434948 | microsome format | Scientific Literature | |
15. | ALA2439925 | A | Ratio of drug level in brain to plasma in C57BL/6 mouse at 10 mg/kg, iv measured at 1 hr | Mus musculus | 6 | ALA2434948 | organism-based format | Scientific Literature | |
16. | ALA2439926 | A | Cmax in C57BL/6 mouse brain at 10 mg/kg, iv | Mus musculus | 6 | ALA2434948 | organism-based format | Scientific Literature |