# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2438478 | A | In vivo calcemic activity in ICR mouse assessed as serum calcium level at 30 mg/kg, sc administered for 7 days (Rvb = 8.76 mg/dL) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
2. | ALA2438479 | A | In vivo calcemic activity in ICR mouse assessed as serum calcium level at 10 mg/kg, sc administered for 7 days (Rvb = 8.76 mg/dL) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
3. | ALA2438480 | A | In vivo calcemic activity in ICR mouse assessed as serum calcium level at 0.5 mg/kg, sc administered for 7 days (Rvb = 8.76 mg/dL) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
4. | ALA2438482 | F | Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
5. | ALA2438485 | F | Cytotoxicity against human HaCaT cells after 48 hrs by MTT assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
6. | ALA2438487 | B | Agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation after 96 hrs by NBT reduction assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
7. | ALA3749447 | B | Agonist activity at vitamin D3 receptor in human HL-60 cells assessed as induction of cell differentiation after 96 hrs by NBT dye-based microscopic analysis | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
8. | ALA3749448 | F | Antipoliferative activity against human PC3 cells after 48 hrs by MTT assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
9. | ALA3749449 | F | Antipoliferative activity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
10. | ALA3749450 | F | Antipoliferative activity against human Caco2 cells after 48 hrs by MTT assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
11. | ALA3749451 | F | Antipoliferative activity against human HepG2 cells after 48 hrs by MTT assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
12. | ALA3749452 | A | Cytotoxicity against human L02 cells after 48 hrs by MTT assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
13. | ALA3749455 | T | Toxicity in rat assessed as hypercalcemic activity at 30 mg/kg/day administered for 7 days | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
14. | ALA4275697 | F | Antiproliferative activity against human BxPC3 cells after 24 hrs by MTT assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
15. | ALA4275698 | F | Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
16. | ALA4275699 | F | Antiproliferative activity against human PC3 cells after 24 hrs by MTT assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
17. | ALA4275700 | B | Displacement of fluormone VDR red from human full-length VDR at 1 uM after 4 hrs by fluorescence polarization assay | Homo sapiens | 40 | single protein format | Scientific Literature | ||
18. | ALA4275701 | B | Displacement of fluormone VDR red from human full-length VDR after 4 hrs by fluorescence polarization assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
19. | ALA4275702 | B | Transactivation of recombinant human VDR/RXRalpha expressed in HEK293 cells after 24 hrs by Dual-luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
20. | ALA4275703 | B | Binding affinity to VDR in scrambled siRNA-transfected human MCF7 cells assessed as cell growth inhibition by measuring reduction in BrdU incorporation after 16 hrs by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature |