| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2438604 | F | Cytotoxicity against human HeLa cells assessed as cell viability at 25 uM after 72 hrs by MTT assay in presence of Escherichia coli NTR and NADPH (Rvb = 67.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA2438605 | F | Cytotoxicity against human HeLa cells assessed as cell viability at 10 uM after 72 hrs by MTT assay in presence of Escherichia coli NTR and NADPH (Rvb = 67.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA2438606 | F | Cytotoxicity against human HeLa cells assessed as cell viability at 1 uM after 72 hrs by MTT assay in presence of Escherichia coli NTR and NADPH (Rvb = 67.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA2438723 | F | Cytotoxicity against human HeLa cells assessed as cell viability at 25 uM after 72 hrs by MTT assay in absence of Escherichia coli NTR and NADPH (Rvb = 88.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA2439166 | F | Cytotoxicity against human HeLa cells assessed as cell viability at 1 uM after 72 hrs by MTT assay in absence of Escherichia coli NTR and NADPH (Rvb = 88.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2439169 | F | Cytotoxicity against human HeLa cells assessed as cell viability at 10 uM after 72 hrs by MTT assay in absence of Escherichia coli NTR and NADPH (Rvb = 88.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2439171 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 10 uM after 72 hrs by MTT assay in presence of Escherichia coli NTR and NADPH (Rvb = 86.3%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA2439172 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 1 uM after 72 hrs by MTT assay in presence of Escherichia coli NTR and NADPH (Rvb = 86.3%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA2439173 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 25 uM after 72 hrs by MTT assay in absence of Escherichia coli NTR and presence of NADPH (Rvb = 74.8%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA2439174 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 10 uM after 72 hrs by MTT assay in absence of Escherichia coli NTR and presence of NADPH (Rvb = 74.8%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA2439175 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 1 uM after 72 hrs by MTT assay in absence of Escherichia coli NTR and presence of NADPH (Rvb = 74.8%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA2439176 | P | Prodrug conversion in phosphate buffer at pH 6.5 assessed as Escherichia coli NTR-mediated decomposition measuring nitric oxide release at 50 uM after 5 mins | Escherichia coli | 1 | small-molecule physicochemical format | Scientific Literature | ||
| 13. | ALA2439177 | P | Prodrug conversion in phosphate buffer at pH 7.4 assessed as Escherichia coli NTR-mediated decomposition measuring nitric oxide release at 50 uM after 5 mins | Escherichia coli | 1 | small-molecule physicochemical format | Scientific Literature | ||
| 14. | ALA2439178 | F | Cytotoxicity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay in presence of Escherichia coli NTR and NADPH | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA2439180 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 25 uM after 72 hrs by MTT assay in presence of Escherichia coli NTR and NADPH (Rvb = 86.3%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA2439181 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 75 uM after 72 hrs by MTT assay in presence of Escherichia coli NTR and NADPH relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA2439182 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 75 uM after 72 hrs by MTT assay in absence of Escherichia coli NTR and presence of NADPH | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 18. | ALA2439183 | P | Stability of the compound in phosphate buffer at pH 7.0 assessed as nitric oxide release at 50 uM after 1 hr by chemiluminescence assay in absence of Escherichia coli NTR and presence of NADPH | 5 | small-molecule physicochemical format | Scientific Literature | |||
| 19. | ALA2439184 | P | Prodrug conversion in phosphate buffer at pH 7.0 assessed as Escherichia coli NTR-mediated decomposition measuring nitric oxide release at 50 uM after 1 hr by chemiluminescence assay in presence of NADPH | Escherichia coli | 5 | small-molecule physicochemical format | Scientific Literature | ||
| 20. | ALA2439185 | P | Prodrug conversion in phosphate buffer at pH 7.0 assessed as Escherichia coli NTR-mediated decomposition measuring compound remaining at 50 uM after 1 hr by HPLC analysis in presence of NADPH | Escherichia coli | 5 | small-molecule physicochemical format | Scientific Literature |
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