# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2439181 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 75 uM after 72 hrs by MTT assay in presence of Escherichia coli NTR and NADPH relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA2439182 | F | Antiproliferative activity against human DLD1 cells assessed as cell viability at 75 uM after 72 hrs by MTT assay in absence of Escherichia coli NTR and presence of NADPH | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
3. | ALA2439183 | P | Stability of the compound in phosphate buffer at pH 7.0 assessed as nitric oxide release at 50 uM after 1 hr by chemiluminescence assay in absence of Escherichia coli NTR and presence of NADPH | 5 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA2439184 | P | Prodrug conversion in phosphate buffer at pH 7.0 assessed as Escherichia coli NTR-mediated decomposition measuring nitric oxide release at 50 uM after 1 hr by chemiluminescence assay in presence of NADPH | Escherichia coli | 5 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA2439185 | P | Prodrug conversion in phosphate buffer at pH 7.0 assessed as Escherichia coli NTR-mediated decomposition measuring compound remaining at 50 uM after 1 hr by HPLC analysis in presence of NADPH | Escherichia coli | 5 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA2439311 | P | Stability of the compound in phosphate buffer at pH 7.0 assessed as compound remaining at 50 uM after 1 hr by HPLC analysis in absence of Escherichia coli NTR and presence of NADPH | 5 | small-molecule physicochemical format | Scientific Literature |