# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2447435 | F | Antiviral activity against Dengue virus 2 infected in human Huh-7 cells assessed as inhibition of viral replication after 48 hrs by luciferase reporter gene assay | dengue virus type 2 | 26 | organism-based format | Scientific Literature | ||
2. | ALA2447436 | A | Permeability of the compound by PAMPA | 27 | assay format | Scientific Literature | |||
3. | ALA2447441 | B | Competitive inhibition of Dengue virus NS2B-NS3 protease expressed in Escherichia coli BL 21 (DE3) using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr as substrate by Cornish-Bowden plot analysis | Dengue virus | 14 | assay format | Scientific Literature | ||
4. | ALA2447442 | B | Inhibition of Dengue virus NS2B-NS3 protease expressed in Escherichia coli BL 21 (DE3) using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr as substrate assessed as enzyme-substrate-inhibitor complex by Cornish-Bowden plot analysis | Dengue virus | 25 | assay format | Scientific Literature | ||
5. | ALA2447443 | B | Inhibition of Dengue virus NS2B-NS3 protease expressed in Escherichia coli BL 21 (DE3) using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr as substrate assessed as enzyme-inhibitor complex by Cornish-Bowden plot analysis | Dengue virus | 25 | assay format | Scientific Literature | ||
6. | ALA2447444 | B | Inhibition of Dengue virus NS2B-NS3 protease expressed in Escherichia coli BL 21 (DE3) using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr as substrate after 15 mins | Dengue virus | 25 | assay format | Scientific Literature | ||
7. | ALA2447445 | B | Inhibition of thrombin (unknown origin) using Boc-Val-Pro-Arg-AMC as substrate at 25 uM after 10 mins by continuous fluorimetric assay | Homo sapiens | 66 | single protein format | Scientific Literature | ||
8. | ALA2447446 | B | Inhibition of West Nile virus NS2B-NS3 protease expressed in Escherichia coli BL 21 (DE3) using Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr as substrate at 50 uM after 15 mins | West Nile virus | 66 | assay format | Scientific Literature | ||
9. | ALA2447447 | B | Inhibition of Dengue virus NS2B-NS3 protease expressed in Escherichia coli BL 21 (DE3) using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr as substrate at 50 uM after 15 mins | Dengue virus | 66 | assay format | Scientific Literature |