| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2446443 | F | Cytotoxicity against human PC3 cells assessed as growth inhibition after 3 days by WST-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA2446445 | B | Antagonist activity at androgen receptor H874Y mutant (unknown origin) expressed in human 22Rv1 cells assessed as inhibition of DHT-induced cell growth after 3 days by WST-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA2446446 | B | Antagonist activity at androgen receptor T877A mutant (unknown origin) expressed in human LNCAP cells assessed as inhibition of DHT-induced cell growth after 6 days by WST-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA2446672 | B | Antagonist activity at androgen receptor in human MDA-kb2 cells assessed as inhibition of DHT-induced luciferase activity at 10 uM after 24 hrs by chemiluminescence assay relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA2446673 | B | Displacement of [3H]-DHT from human GST-tagged androgen receptor LBD (627 to 919) expressed in Escherichia coli HB-101 after 15 hrs by liquid scintillation counting analysis | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 6. | ALA2446674 | B | Antagonist activity at androgen receptor in mouse SC3 cells assessed as inhibition of DHT-induced cell growth after 3 days by CCK-8/WST-8 assay | Mus musculus | 19 | cell-based format | Scientific Literature | ||
| 7. | ALA3867362 | B | Antagonist activity at progesterone receptor in human T47D cells incubated for 24 hrs in presence of P4 by alkaline phosphatase assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
| 8. | ALA3867363 | B | Agonist activity at progesterone receptor in human T47D cells measured after 24 hrs by alkaline phosphatase assay | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
| 9. | ALA3867366 | B | Antagonist activity at androgen receptor in human SC-3 cells assessed as inhibition of DHT-induced cell growth at 1 uM co-treated with DHT measured after 3 days by CCK8 assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 10. | ALA4035630 | A | Transactivation of human GRalpha expressed in HEK293 cells after 24 hrs by luciferase reporter gene assay | Homo sapiens | 41 | cell-based format | Scientific Literature | ||
| 11. | ALA4035631 | B | Antagonist activity at human GRalpha expressed in HEK293 cells assessed as inhibition of dexamethasone-induced response after 24 hrs by luciferase reporter gene assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 12. | ALA4158079 | B | Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation at 10 uM after 3 days by CCK8 assay relative to control | Mus musculus | 17 | cell-based format | Scientific Literature | ||
| 13. | ALA4158080 | B | Antagonist activity at AR in mouse SC3 cells assessed as inhibition of DHT-induced cell proliferation after 3 days by CCK8 assay | Mus musculus | 26 | cell-based format | Scientific Literature | ||
| 14. | ALA4158083 | B | Antagonist activity at AR T877A mutant in human LNCAP cells assessed as inhibition of DHT-induced cell proliferation treated for 3 days followed by compound washout and supplemented with fresh medium containing compound measured after 3 days by WST8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 15. | ALA4158084 | B | Antagonist activity at AR H874Y mutant in human 22Rv1 cells assessed as inhibition of DHT-induced cell proliferation measured after 3 days by WST8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 16. | ALA4158085 | F | Antiproliferative activity against human PC3 cells assessed as inhibition of cell proliferation after 3 days in presence of DHT by WST8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 17. | ALA5140965 | F | Antiproliferative activity against mouse SC-3 cells | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA5140967 | F | Antiproliferative activity against human LNCaP cells expressing Androgen receptor T887A mutant | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5140968 | F | Antiproliferative activity against human 22Rv1 cells expressing Androgen receptor H874Y mutant | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5140969 | F | Antiproliferative activity against androgen-independent human PC-3 cells | Homo sapiens | 1 | cell-based format | Scientific Literature |
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