# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2447063 | ADME | Half life in human liver microsomes | Homo sapiens | 5 | ALA2440116 | microsome format | Scientific Literature | |
2. | ALA2447064 | ADME | Half life in CD-1 mouse liver microsomes | Mus musculus | 5 | ALA2440116 | microsome format | Scientific Literature | |
3. | ALA2447067 | ADME | Therapeutic index, ratio of EC50 for african green monkey Vero cells to MIC for Mycobacterium tuberculosis H37Rv | 26 | ALA2440116 | cell-based format | Scientific Literature | ||
4. | ALA2447068 | ADME | Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay | Chlorocebus sabaeus | 35 | ALA2440116 | cell-based format | Scientific Literature | |
5. | ALA2447069 | Functional | Antitubercular activity against Mycobacterium tuberculosis H37Rv in GAST media with glycerol and alanine after 7 to 14 days by broth microdilution method | Mycobacterium tuberculosis | 79 | ALA2440116 | organism-based format | Scientific Literature | |
6. | ALA2447070 | Functional | Antitubercular activity against Mycobacterium tuberculosis H37Rv in Middlebrook 7H9 broth with butyrate after 7 to 14 days by broth microdilution method | Mycobacterium tuberculosis | 69 | ALA2440116 | organism-based format | Scientific Literature | |
7. | ALA2447071 | Functional | Antitubercular activity against Mycobacterium tuberculosis H37Rv in Middlebrook 7H9 broth with glucose after 7 to 14 days by broth microdilution method | Mycobacterium tuberculosis | 79 | ALA2440116 | organism-based format | Scientific Literature | |
8. | ALA3106744 | Toxicity | Selectivity index, ratio of IC50 for CHO cells to IC50 for chloroquine-sensitive asexual erythrocytic stage of Plasmodium falciparum NF54 | 28 | ALA3102791 | cell-based format | Scientific Literature | ||
9. | ALA3106745 | ADME | Cytotoxicity against CHO cells by MTT assay | Cricetulus griseus | 28 | ALA3102791 | cell-based format | Scientific Literature | |
10. | ALA3106746 | Functional | Antiplasmodial activity against chloroquine-sensitive asexual erythrocytic stage of Plasmodium falciparum NF54 assessed as parasite growth inhibition by lactate dehydrogenase assay | Plasmodium falciparum | 28 | ALA3102791 | organism-based format | Scientific Literature | |
11. | ALA3106747 | Physicochemical | Solubility of the compound in PBS buffer at pH 7.4 after 2 hrs by turbidimetric analysis | 28 | ALA3102791 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA3106748 | Functional | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv assessed as growth inhibition after 7 to 14 days by broth microdilution method | Mycobacterium tuberculosis | 28 | ALA3102791 | organism-based format | Scientific Literature |