# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2447651 | F | Induction of natriuresis in Sprague-Dawley rat at 10 mg/kg, po relative to vehicle-treated control | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
2. | ALA2447652 | F | Induction of diuresis in Sprague-Dawley rat at 10 mg/kg, po relative to vehicle-treated control | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
3. | ALA2447653 | A | Oral bioavailability in Sprague-Dawley rat 2 mg/kg | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
4. | ALA2447654 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
5. | ALA2447655 | A | Dose normalized AUC in Sprague-Dawley rat 2 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
6. | ALA2447656 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
7. | ALA2447657 | A | Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
8. | ALA2447658 | B | Inhibition of rat ROMK channel-mediated 86Rb+ flux | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
9. | ALA2447659 | B | Inhibition of Cav1.2 channel (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA2447660 | B | Inhibition of serotonin transporter (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA2443472 | B | Inhibition of Nav1.5 channel (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA2443473 | B | Inhibition of Kir7.1 channel (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA2443474 | B | Inhibition of Kir4.1 channel (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA2443475 | B | Inhibition of Kir2.3 channel (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA2443476 | B | Inhibition of Kir2.1 channel (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA2443477 | B | Selectivity ratio of IC50 for human ERG to IC50 for human ROMK channel by electrophysiology assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
17. | ALA2443478 | B | Inhibition of human ROMK channel by electrophysiology assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
18. | ALA2443479 | B | Inhibition of human ERG by electrophysiology assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
19. | ALA2443480 | B | Selectivity ratio of IC50 for human ERG to IC50 for human ROMK channel | Homo sapiens | 5 | assay format | Scientific Literature | ||
20. | ALA2443482 | B | Displacement of [35S]-MK499 from human ERG | Homo sapiens | 33 | single protein format | Scientific Literature |