# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2446557 | F | Increase of histamine release in Wistar rat hypothalamus at 10 uM administered through dialysis membrane by HPLC-fluorometric based microdialysis relative to control | Rattus norvegicus | 6 | organism-based format | Scientific Literature | ||
2. | ALA2446558 | F | Antagonist activity at human histamine H4 receptor expressed in CHO cells assessed inhibition of forskolin/histamine-induced cAMP accumulation at 1 uM after 1.5 hrs by TR-FRET immunoassay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
3. | ALA2446559 | F | Agonist activity at human histamine H4 receptor expressed in CHO cells assessed increase of forskolin-induced cAMP accumulation at 1 uM after 1.5 hrs by TR-FRET immunoassay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA2446560 | F | Antagonist activity at human histamine H3 receptor expressed in CHO cells assessed as inhibition of forskolin/R-alpha-methylhistamine-induced cAMP accumulation after 1.5 hrs by TR-FRET immunoassay | Homo sapiens | 18 | cell-based format | Scientific Literature |