| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2444793 | A | Downregulation of cyclin E protein expression in TdT-deficient human HeLa cells at 30 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA2444794 | F | Downregulation of cyclin E protein expression in human MOLT4 cells overexpressing TdT at 30 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA2445046 | A | Cell cycle arrest in TdT-deficient human HeLa cells assessed as decrease of cells in G2 phase at 30 uM after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis relative to vehicle-treated control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA2445047 | A | Cell cycle arrest in TdT-deficient human HeLa cells assessed as accumulation at G1 phase at 30 uM after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis relative to vehicle-treated control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA2445048 | A | Cytotoxicity against TdT-deficient human HeLa cells assessed as growth inhibition after 24 to 48 hrs by MTT assay | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 6. | ALA2445049 | F | Cytotoxicity against human MOLT4 cells overexpressing TdT assessed as growth inhibition after 24 to 48 hrs by MTT assay | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 7. | ALA2445054 | B | Inhibition of human recombinant DNA polymerase beta | Homo sapiens | 50 | single protein format | Scientific Literature | ||
| 8. | ALA2445055 | B | Inhibition of human recombinant full length DNA polymerase lambda TdT-like activity using [3H]dNTP as substrate after 10 mins by scintillation counting analysis | Homo sapiens | 50 | single protein format | Scientific Literature | ||
| 9. | ALA2445056 | B | Inhibition of human recombinant full length DNA polymerase lambda using [3H]dTTP as substrate and 10 poly(dA)/oligo(dT) as template-primer after 15 mins by scintillation counting analysis | Homo sapiens | 50 | single protein format | Scientific Literature | ||
| 10. | ALA2445057 | B | Inhibition of human recombinant TdT using [3H]dNTP as substrate after 10 mins by scintillation counting analysis | Homo sapiens | 50 | single protein format | Scientific Literature | ||
| 11. | ALA2445058 | F | Cell cycle arrest in human MOLT4 cells overexpressing TdT assessed as accumulation at G1 phase at 30 uM after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis relative to vehicle-treated control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA2445059 | F | Cell cycle arrest in human MOLT4 cells overexpressing TdT assessed as decrease of cells in G2 phase at 30 uM after 24 hrs by propidium iodide staining-based FACS flow cytometric analysis relative to vehicle-treated control | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!