# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2444912 | F | Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as reduction of bax mRNA at 5 to 10 uM after 2 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
2. | ALA2444913 | F | Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as reduction of bcl2 mRNA at 5 to 10 uM after 2 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
3. | ALA2444916 | F | Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as reduction of mRNA ratio of bcl2 to bax at 5 to 10 uM after 2 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
4. | ALA2444918 | A | Cytotoxicity against Sprague-Dawley rat embryo cortex NSC assessed as shrinkage and rounding up of cells at 20 to 50 uM after 2 days by microscopy relative to DMSO-treated control in presence of EGF and FGF2 | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
5. | ALA2444919 | A | Cytotoxicity against Sprague-Dawley rat embryo cortex NSC assessed as cell viability at 1 to 50 uM after 2 days by MTT assay relative to DMSO-treated control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
6. | ALA2444920 | F | Antiproliferative activity against Sprague-Dawley rat embryo cortex NSC assessed as reduction in neurosphere volume at 5 to 10 uM after 5 days by neurosphere growth assay relative to DMSO-treated control in presence of EGF and FGF2 | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
7. | ALA2444921 | F | Inhibition of astrocytogenesis of Sprague-Dawley rat embryo cortex NSC assessed as downregulation of hes1 mRNA expression after 4 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
8. | ALA2444922 | F | Inhibition of astrocytogenesis of Sprague-Dawley rat embryo cortex NSC assessed as downregulation of notch1 mRNA expression after 4 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
9. | ALA2444923 | F | Inhibition of astrocytogenesis of Sprague-Dawley rat embryo cortex NSC assessed as repression of gfap mRNA expression after 4 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
10. | ALA2444924 | F | Induction of neurogenesis of Sprague-Dawley rat embryo cortex NSC assessed as increase in neuroD mRNA expression after 4 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
11. | ALA2445154 | F | Induction of neurogenesis of Sprague-Dawley rat embryo cortex NSC assessed as increase in beta3 tubulin mRNA expression after 4 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
12. | ALA2445156 | F | Induction of neurogenesis of Sprague-Dawley rat embryo cortex NSC assessed as effect on morphology at 10 uM after 4 days by DAPI-based phase-contrast microscopy relative to DMSO-treated control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
13. | ALA2445157 | F | Induction of neurogenesis of Sprague-Dawley rat embryo cortex NSC assessed as increase in beta3 tubulin mRNA expression at 5 uM after 4 days by RT-PCR method relative to DMSO-treated control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
14. | ALA2445158 | F | Induction of differentiation of Sprague-Dawley rat embryo cortex NSC assessed as TUJ1-positive neurons at 5 uM after 4 days by immunostaining method relative to DMSO-treated control | Rattus norvegicus | 27 | cell-based format | Scientific Literature |