# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2445544 | ADME | Metabolic stability in rat liver S9 fraction assessed as formation of {4-[4-(1-Oxo-1lambda4-thiiran-2-ylmethanesulfonyl)-phenoxy]-phenyl}-carbamic acid methyl ester at 50 uM after 30 mins by reversed-phase LC/MS analysis | Rattus norvegicus | 1 | ALA2440018 | subcellular format | Scientific Literature | |
2. | ALA2445545 | ADME | Metabolic stability in rat liver S9 fraction assessed as formation of 4-(4-(methoxycarbonylamino)phenoxy)benzenesulfinic acid at 50 uM after 30 mins by reversed-phase LC/MS analysis | Rattus norvegicus | 1 | ALA2440018 | subcellular format | Scientific Literature | |
3. | ALA2445546 | ADME | Metabolic stability in rat liver S9 fraction assessed as formation of 4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)aniline at 50 uM after 30 mins by reversed-phase LC/MS analysis | Rattus norvegicus | 1 | ALA2440018 | subcellular format | Scientific Literature | |
4. | ALA2445789 | ADME | Half life in rat liver S9 fraction at 10 uM by reversed-phase UPLC/ESI-MRM analysis | Rattus norvegicus | 5 | ALA2440018 | subcellular format | Scientific Literature | |
5. | ALA2445792 | Binding | Selectivity ratio of Ki for human recombinant MMP-9 catalytic domain to Ki for human recombinant MMP-2 | Homo sapiens | 16 | ALA2440018 | assay format | Scientific Literature | |
6. | ALA2445794 | Binding | Inhibition of human recombinant MMP-8 catalytic domain using McaKPLGL9(Dpa)AR-NH2 as substrate by fluorescence spectrophotometric analysis | Homo sapiens | 16 | ALA2440018 | single protein format | Scientific Literature | |
7. | ALA2445795 | Binding | Inhibition of human recombinant MMP-7 at 50 uM by fluorescence spectrophotometric analysis relative to control | Homo sapiens | 16 | ALA2440018 | single protein format | Scientific Literature | |
8. | ALA2445796 | Binding | Inhibition of human recombinant MMP-3 catalytic domain at 50 uM by fluorescence spectrophotometric analysis relative to control | Homo sapiens | 15 | ALA2440018 | single protein format | Scientific Literature | |
9. | ALA2445797 | Binding | Inhibition of human recombinant MMP-1 catalytic domain at 50 uM by fluorescence spectrophotometric analysis relative to control | Homo sapiens | 16 | ALA2440018 | single protein format | Scientific Literature | |
10. | ALA2445799 | Binding | Inhibition of human recombinant MMP-14 catalytic domain using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysis | Homo sapiens | 12 | ALA2440018 | single protein format | Scientific Literature | |
11. | ALA2446581 | Binding | Inhibition of human recombinant MMP-9 catalytic domain using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysis | Homo sapiens | 12 | ALA2440018 | single protein format | Scientific Literature | |
12. | ALA2446582 | Binding | Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysis | Homo sapiens | 17 | ALA2440018 | single protein format | Scientific Literature |