# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2443547 | F | Induction of DNA repair in Saccharomyces cerevisiae W3749-14C harboring Rad52-YFP assessed as increase in Rad52 foci formation at 100 uM after 3 hrs | Saccharomyces cerevisiae | 4 | ALA2439982 | organism-based format | Scientific Literature | |
2. | ALA2443548 | F | Cell cycle arrest in Saccharomyces cerevisiae W3749-14C harboring RAD52-YFP assessed as accumulation at G2 Phase at 100 uM after 3 hrs | Saccharomyces cerevisiae | 4 | ALA2439982 | organism-based format | Scientific Literature | |
3. | ALA2443550 | F | Growth inhibition of Saccharomyces cerevisiae FM588 expressing wild type rad52 gene at 1 to 100 uM after 24 hrs by spectrophotometry | Saccharomyces cerevisiae | 5 | ALA2439982 | organism-based format | Scientific Literature | |
4. | ALA2443551 | B | Inhibition of Xanthomonas vasicola Xho1 assessed as inhibition of endonucleolytic cleavage of pBSKS plasmid DNA at 100 uM by agarose gel electrophoresis | Xanthomonas vasicola | 1 | ALA2439982 | single protein format | Scientific Literature | |
5. | ALA2443552 | B | Inhibition of DNA topoisomerase 1 (unknown origin)-mediated relaxation of supercoiled pBSKS plasmid DNA assessed as formation of nicked form of DNA at 1 00 uM after 30 mins by agarose gel electrophoresis in presence of ethidium bromide | Homo sapiens | 8 | ALA2439982 | single protein format | Scientific Literature | |
6. | ALA2443553 | B | Inhibition of DNA topoisomerase 1 (unknown origin)-mediated DNA cleavage assessed as decrease in relaxation of supercoiled pBSKS plasmid at 1 00 uM after 30 mins by agarose gel electrophoresis | Homo sapiens | 3 | ALA2439982 | single protein format | Scientific Literature | |
7. | ALA2443555 | B | Inhibition of human DNA topoisomerase 2alpha-mediated DNA cleavage assessed as decrease in relaxation of supercoiled pRYG plasmid at 60 uM after 30 mins by agarose gel electrophoresis | Homo sapiens | 4 | ALA2439982 | single protein format | Scientific Literature | |
8. | ALA2443556 | B | Inhibition of human DNA topoisomerase 2alpha-mediated relaxation of supercoiled pRYG plasmid DNA assessed as formation of linearized DNA at 100 uM after 30 mins by agarose gel electrophoresis relative to vehicle-treated control in presence of ethidium bromide | Homo sapiens | 7 | ALA2439982 | single protein format | Scientific Literature | |
9. | ALA2443824 | F | Antiproliferative activity against human HEL cells after 48 hrs by MTT assay | Homo sapiens | 7 | ALA2439982 | cell-based format | Scientific Literature | |
10. | ALA2443825 | F | Antiproliferative activity against human SKBR3 cells after 48 hrs by MTT assay | Homo sapiens | 15 | ALA2439982 | cell-based format | Scientific Literature | |
11. | ALA2443826 | F | Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 9 | ALA2439982 | cell-based format | Scientific Literature |